Immunogenicity 15827

summary
Sample ID
3998
Response
Positive
Tumor Type
Melanoma
Gene Symbol
MED13
Transcript ID
None
HLA INFO
B*15:01
TCR INFO

No TCR info found!

T cell Tumor cell B*15:01
sequence
Full length protein sequence (2121 aa)
MSASF
1
VPNGA
6
SLEDC
11
HCNLF
16
CLADL
21
TGIKW
26
KKYVW
31
QGPTS
36
APILF
41
PVTEE
46
DPILS
51
SFSRC
56
LKADV
61
LGVWR
66
RDQRP
71
GRREL
76
WIFWW
81
GEDPS
86
FADLI
91
HHDLS
96
EEEDG
101
VWENG
106
LSYEC
111
RTLLF
116
KAVHN
121
LLERC
126
LMNRN
131
FVRIG
136
KWFVK
141
PYEKD
146
EKPIN
151
KSEHL
156
SCSFT
161
FFLHG
166
DSNVC
171
TSVEI
176
NQHQP
181
VYLLS
186
EEHIT
191
LAQQS
196
NSPFQ
201
VILCP
206
FGLNG
211
TLTGQ
216
AFKMS
221
DSATK
226
KLIGE
231
WKQFY
236
PISCC
241
LKEMS
246
EEKQE
251
DMDWE
256
DDSLA
261
AVEVL
266
VAGVR
271
MIYPA
276
CFVLV
281
PQSDI
286
PTPSP
291
VGSTH
296
CSSSC
301
LGVHQ
306
VPAST
311
RDPAM
316
SSVTL
321
TPPTS
326
PEEVQ
331
TVDPQ
336
SVQKW
341
VKFSS
346
VSDGF
351
NSDST
356
SHHGG
361
KIPRK
366
LANHV
371
VDRVW
376
QECNM
381
NRAQN
386
KRKYS
391
ASSGG
396
LCEEA
401
TAAKV
406
ASWDF
411
VEATQ
416
RTNCS
421
CLRHK
426
NLKSR
431
NAGQQ
436
GQAPS
441
LGQQQ
446
QILPK
451
HKTNE
456
KQEKS
461
EKPQK
466
RPLTP
471
FHHRV
476
SVSDD
481
VGMDA
486
DSASQ
491
RLVIS
496
APDSQ
501
VRFSN
506
IRTND
511
VAKTP
516
QMHGT
521
EMANS
526
PQPPP
531
LSPHP
536
CDVVD
541
EGVTK
546
TPSTP
551
QSQHF
556
YQMPT
561
PDPLV
566
PSKPM
571
EDRID
576
SLSQS
581
FPPQY
586
QEAVE
591
PTVYV
596
GTAVN
601
LEEDE
606
ANIAW
611
KYYKF
616
PKKKD
621
VEFLP
626
PQLPS
631
DKFKD
636
DPVGP
641
FGQES
646
VTSVT
651
ELMVQ
656
CKKPL
661
KVSDE
666
LVQQY
671
QIKNQ
676
CLSAI
681
ASDAE
686
QEPKI
691
DPYAF
696
VEGDE
701
EFLFP
706
DKKDR
711
QNSER
716
EAGKK
721
HKVED
726
GTSSV
731
TVLSH
736
EEDAM
741
SLFSP
746
SIKQD
751
APRPT
756
SHARP
761
PSTSL
766
IYDSD
771
LAVSY
776
TDLDN
781
LFNSD
786
EDELT
791
PGSKK
796
SANGS
801
DDKAS
806
CKESK
811
TGNLD
816
PLSCI
821
STADL
826
HKMYP
831
TPPSL
836
EQHIM
841
GFSPM
846
NMNNK
851
EYGSM
856
DTTPG
861
GTVLE
866
GNSSS
871
IGAQF
876
KIEVD
881
EGFCS
886
PKPSE
891
IKDFS
896
YVYKP
901
ENCQI
906
LVGCS
911
MFAPL
916
KTLPS
921
QYLPP
926
IKLPE
931
ECIYR
936
QSWTV
941
GKLEL
946
LSSGP
951
SMPFI
956
KEGDG
961
SNMDQ
966
EYGTA
971
YTPQT
976
HTSFG
981
MPPSS
986
APPSN
991
SGAGI
996
LPSPS
1001
TPRFP
1006
TPRTP
1011
RTPRT
1016
PRGAG
1021
GPASA
1026
QGSVK
1031
YENSD
1036
LYSPA
1041
STPST
1046
CRPLN
1051
SVEPA
1056
TVPSI
1061
PEAHS
1066
LYVNL
1071
ILSES
1076
VMNLF
1081
KDCNF
1086
DSCCI
1091
CVCNM
1096
NIKGA
1101
DVGVY
1106
IPDPT
1111
QEAQY
1116
RCTCG
1121
FSAVM
1126
NRKFG
1131
NNSGL
1136
FLEDE
1141
LDIIG
1146
RNTDC
1151
GKEAE
1156
KRFEA
1161
LRATS
1166
AEHVN
1171
GGLKE
1176
SEKLS
1181
DDLIL
1186
LLQDQ
1191
CTNLF
1196
SPFGA
1201
ADQDP
1206
FPKSG
1211
VISNW
1216
VRVEE
1221
RDCCN
1226
DCYLA
1231
LEHGR
1236
QFMDN
1241
MSGGK
1246
VDEAL
1251
VKSSC
1256
LHPWS
1261
KRNDV
1266
SMQCS
1271
QDILR
1276
MLLSL
1281
QPVLQ
1286
DAIQK
1291
KRTVR
1296
PWGVQ
1301
GPLTW
1306
QQFHK
1311
MAGRG
1316
SYGTD
1321
ESPEP
1326
LPIPT
1331
FLLGY
1336
DYDYL
1341
VLSPF
1346
ALPYW
1351
ERLML
1356
EPYGS
1361
QRDIA
1366
YVVLC
1371
PENEA
1376
LLNGA
1381
KSFFR
1386
DLTAI
1391
YESCR
1396
LGQHR
1401
PVSRL
1406
LTDGI
1411
MRVGS
1416
TASKK
1421
LSEKL
1426
VAEWF
1431
SQAAD
1436
GNNEA
1441
FSKLK
1446
LYAQV
1451
CRYDL
1456
GPYLA
1461
SLPLD
1466
SSLLS
1471
QPNLV
1476
APTSQ
1481
SLITP
1486
PQMTN
1491
TGNAN
1496
TPSAT
1501
LASAA
1506
SSTMT
1511
VTSGV
1516
AISTS
1521
VATAN
1526
STLTT
1531
ASTSS
1536
SSSSN
1541
LNSGV
1546
SSNKL
1551
PSFPP
1556
FGSMN
1561
SNAAG
1566
SMSTQ
1571
ANTVQ
1576
SGQLG
1581
GQQTS
1586
ALQTA
1591
GISGE
1596
SSSLP
1601
TQPHP
1606
DVSES
1611
TMDRD
1616
KVGIP
1621
TDGDS
1626
HAVTY
1631
PPAIV
1636
VYIID
1641
PFTYE
1646
NTDES
1651
TNSSS
1656
VWTLG
1661
LLRCF
1666
LEMVQ
1671
TLPPH
1676
IKSTV
1681
SVQII
1686
PCQYL
1691
LQPVK
1696
HEDRE
1701
IYPQH
1706
LKSLA
1711
FSAFT
1716
QCRRP
1721
LPTST
1726
NVKTL
1731
TGFGP
1736
GLAME
1741
TALRS
1746
PDRPE
1751
CIRLY
1756
APPFI
1761
LAPVK
1766
DKQTE
1771
LGETF
1776
GEAGQ
1781
KYNVL
1786
FVGYC
1791
LSHDQ
1796
RWILA
1801
SCTDL
1806
YGELL
1811
ETCII
1816
NIDVP
1821
NRARR
1826
KKSSA
1831
RKFGL
1836
QKLWE
1841
WCLGL
1846
VQMSS
1851
LPWRV
1856
VIGRL
1861
GRIGH
1866
GELKD
1871
SVSTG
1876
SVFGR
1881
STTLN
1886
MQTSQ
1891
LNTPQ
1896
DTSCT
1901
HILVF
1906
PTSAS
1911
VQVAS
1916
ATYTT
1921
ENLDL
1926
AFNPN
1931
NDGAD
1936
GMGIF
1941
DLLDT
1946
GDDLD
1951
PDIIN
1956
ILPAS
1961
PTGSP
1966
VHSPG
1971
SHYPH
1976
GGDAG
1981
KGQST
1986
DRLLS
1991
TEPHE
1996
EVPNI
2001
LQQPL
2006
ALGYF
2011
VSTAK
2016
AGPLP
2021
DWFWS
2026
ACPQA
2031
QYQCP
2036
LFLKA
2041
SLHLH
2046
VPSVQ
2051
SDELL
2056
HSKHS
2061
HPLDS
2066
NQTSD
2071
VLRFV
2076
LEQYN
2081
ALSWL
2086
TCDPA
2091
TQDRR
2096
SCLPI
2101
HFVVL
2106
NQLYN
2111
FIMNM
2116
L
2121
Mutation Information
DNA mutation:
None
Peptide Range:
1687 ~ 1694
Mut AA position:
1691 (5 in Wild Type peptide)
Alignment
Wild Type:
"VQIIPCQY
||||.|||
Mutant:
VQIISCQY"
reference
clinic trial
Checkpoint Blockade

None

ACT

Y

Vaccination

N

Curative Effect

non responder

experiment
minimal_peptide

Y

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

None