Immunogenicity 15848

summary
Sample ID
patient1
Response
Positive
Tumor Type
Melanoma
Gene Symbol
GCN1 (FPKM: 37.8)
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (2671 aa)
MAADT
1
QVSET
6
LKRFA
11
GKVTT
16
ASVKE
21
RREIL
26
SELGK
31
CVAGK
36
DLPEG
41
AVKGL
46
CKLFC
51
LTLHR
56
YRDAA
61
SRRAL
66
QAAIQ
71
QLAEA
76
QPEAT
81
AKNLL
86
HSLQS
91
SGIGS
96
KAGVP
101
SKSSG
106
SAALL
111
ALTWT
116
CLLVR
121
IVFPS
126
RAKRQ
131
GDIWN
136
KLVEV
141
QCLLL
146
LEVLG
151
GSHKH
156
AVDGA
161
VKKLT
166
KLWKE
171
NPGLV
176
EQYLS
181
AILSL
186
EPNQN
191
YAGML
196
GLLVQ
201
FCTSH
206
KEMDV
211
VSQHK
216
SALLD
221
FYMKN
226
ILMSK
231
VKPPK
236
YLLDS
241
CAPLL
246
RYLSH
251
SEFKD
256
LILPT
261
IQKSL
266
LRSPE
271
NVIET
276
ISSLL
281
ASVTL
286
DLSQY
291
AMDIV
296
KGLAG
301
HLKSN
306
SPRLM
311
DEAVL
316
ALRNL
321
ARQCS
326
DSSAM
331
ESLTK
336
HLFAI
341
LGGSE
346
GKLTV
351
VAQKM
356
SVLSG
361
IGSVS
366
HHVVS
371
GPSSQ
376
VLNGI
381
VAELF
386
IPFLQ
391
QEVHE
396
GTLVH
401
AVSVL
406
ALWCN
411
RFTME
416
VPKKL
421
TEWFK
426
KAFSL
431
KTSTS
436
AVRHA
441
YLQCM
446
LASYR
451
GDTLL
456
QALDL
461
LPLLI
466
QTVEK
471
AASQS
476
TQVPT
481
ITEGV
486
AAALL
491
LLKLS
496
VADSQ
501
AEAKL
506
SSFWQ
511
LIVDE
516
KKQVF
521
TSEKF
526
LVMAS
531
EDALC
536
TVLHL
541
TERLF
546
LDHPH
551
RLTGN
556
KVQQY
561
HRALV
566
AVLLS
571
RTWHV
576
RRQAQ
581
QTVRK
586
LLSSL
591
GGFKL
596
AHGLL
601
EELKT
606
VLSSH
611
KVLPL
616
EALVT
621
DAGEV
626
TEAGK
631
AYVPP
636
RVLQE
641
ALCVI
646
SGVPG
651
LKGDV
656
TDTEQ
661
LAQEM
666
LIISH
671
HPSLV
676
AVQSG
681
LWPAL
686
LARMK
691
IDPEA
696
FITRH
701
LDQII
706
PRMTT
711
QSPLN
716
QSSMN
721
AMGSL
726
SVLSP
731
DRVLP
736
QLIST
741
ITASV
746
QNPAL
751
RLVTR
756
EEFAI
761
MQTPA
766
GELYD
771
KSIIQ
776
SAQQD
781
SIKKA
786
NMKRE
791
NKAYS
796
FKEQI
801
IELEL
806
KEEIK
811
KKKGI
816
KEEVQ
821
LTSKQ
826
KEMLQ
831
AQLDR
836
EAQVR
841
RRLQE
846
LDGEL
851
EAALG
856
LLDII
861
LAKNP
866
SGLTQ
871
YIPVL
876
VDSFL
881
PLLKS
886
PLAAP
891
RIKNP
896
FLSLA
901
ACVMP
906
SRLKA
911
LGTLV
916
SHVTL
921
RLLKP
926
ECVLD
931
KSWCQ
936
EELSV
941
AVKRA
946
VMLLH
951
THTIT
956
SRVGK
961
GEPGA
966
APLSA
971
PAFSL
976
VFPFL
981
KMVLT
986
EMPHH
991
SEEEE
996
EWMAQ
1001
ILQIL
1006
TVQAQ
1011
LRASP
1016
NTPPG
1021
RVDEN
1026
GPELL
1031
PRVAM
1036
LRLLT
1041
WVIGT
1046
GSPRL
1051
QVLAS
1056
DTLTT
1061
LCASS
1066
SGDDG
1071
CAFAE
1076
QEEVD
1081
VLLCA
1086
LQSPC
1091
ASVRE
1096
TVLRG
1101
LMELH
1106
MVLPA
1111
PDTDE
1116
KNGLN
1121
LLRRL
1126
WVVKF
1131
DKEEE
1136
IRKLA
1141
ERLWS
1146
MMGLD
1151
LQPDL
1156
CSLLI
1161
DDVIY
1166
HEAAV
1171
RQAGA
1176
EALSQ
1181
AVARY
1186
QRQAA
1191
EVMGR
1196
LMEIY
1201
QEKLY
1206
RPPPV
1211
LDALG
1216
RVISE
1221
SPPDQ
1226
WEARC
1231
GLALA
1236
LNKLS
1241
QYLDS
1246
SQVKP
1251
LFQFF
1256
VPDAL
1261
NDRHP
1266
DVRKC
1271
MLDAA
1276
LATLN
1281
THGKE
1286
NVNSL
1291
LPVFE
1296
EFLKN
1301
APNDA
1306
SYDAV
1311
RQSVV
1316
VLMGS
1321
LAKHL
1326
DKSDP
1331
KVKPI
1336
VAKLI
1341
AALST
1346
PSQQV
1351
QESVA
1356
SCLPP
1361
LVPAI
1366
KEDAG
1371
GMIQR
1376
LMQQL
1381
LESDK
1386
YAERK
1391
GAAYG
1396
LAGLV
1401
KGLGI
1406
LSLKQ
1411
QEMMA
1416
ALTDA
1421
IQDKK
1426
NFRRR
1431
EGALF
1436
AFEML
1441
CTMLG
1446
KLFEP
1451
YVVHV
1456
LPHLL
1461
LCFGD
1466
GNQYV
1471
REAAD
1476
DCAKA
1481
VMSNL
1486
SAHGV
1491
KLVLP
1496
SLLAA
1501
LEEES
1506
WRTKA
1511
GSVEL
1516
LGAMA
1521
YCAPK
1526
QLSSC
1531
LPNIV
1536
PKLTE
1541
VLTDS
1546
HVKVQ
1551
KAGQQ
1556
ALRQI
1561
GSVIR
1566
NPEIL
1571
AIAPV
1576
LLDAL
1581
TDPSR
1586
KTQKC
1591
LQTLL
1596
DTKFV
1601
HFIDA
1606
PSLAL
1611
IMPIV
1616
QRAFQ
1621
DRSTD
1626
TRKMA
1631
AQIIG
1636
NMYSL
1641
TDQKD
1646
LAPYL
1651
PSVTP
1656
GLKAS
1661
LLDPV
1666
PEVRT
1671
VSAKA
1676
LGAMV
1681
KGMGE
1686
SCFED
1691
LLPWL
1696
METLT
1701
YEQSS
1706
VDRSG
1711
AAQGL
1716
AEVMA
1721
GLGVE
1726
KLEKL
1731
MPEIV
1736
ATASK
1741
VDIAP
1746
HVRDG
1751
YIMMF
1756
NYLPI
1761
TFGDK
1766
FTPYV
1771
GPIIP
1776
CILKA
1781
LADEN
1786
EFVRD
1791
TALRA
1796
GQRVI
1801
SMYAE
1806
TAIAL
1811
LLPQL
1816
EQGLF
1821
DDLWR
1826
IRFSS
1831
VQLLG
1836
DLLFH
1841
ISGVT
1846
GKMTT
1851
ETASE
1856
DDNFG
1861
TAQSN
1866
KAIIT
1871
ALGVE
1876
RRNRV
1881
LAGLY
1886
MGRSD
1891
TQLVV
1896
RQASL
1901
HVWKI
1906
VVSNT
1911
PRTLR
1916
EILPT
1921
LFGLL
1926
LGFLA
1931
STCAD
1936
KRTIA
1941
ARTLG
1946
DLVRK
1951
LGEKI
1956
LPEII
1961
PILEE
1966
GLRSQ
1971
KSDER
1976
QGVCI
1981
GLSEI
1986
MKSTS
1991
RDAVL
1996
YFSES
2001
LVPTA
2006
RKALC
2011
DPLEE
2016
VREAA
2021
AKTFE
2026
QLHST
2031
IGHQA
2036
LEDIL
2041
PFLLK
2046
QLDDE
2051
EVSEF
2056
ALDGL
2061
KQVMA
2066
IKSRV
2071
VLPYL
2076
VPKLT
2081
TPPVN
2086
TRVLA
2091
FLSSV
2096
AGDAL
2101
TRHLG
2106
VILPA
2111
VMLAL
2116
KEKLG
2121
TPDEQ
2126
LEMAN
2131
CQAVI
2136
LSVED
2141
DTGHR
2146
IIIED
2151
LLEAT
2156
RSPEV
2161
GMRQA
2166
AAIIL
2171
NIYCS
2176
RSKAD
2181
YTSHL
2186
RSLVS
2191
GLIRL
2196
FNDSS
2201
PVVLE
2206
ESWDA
2211
LNAIT
2216
KKLDA
2221
GNQLA
2226
LIEEL
2231
HKEIR
2236
LIGNE
2241
SKGEH
2246
VPGFC
2251
LPKKG
2256
VTSIL
2261
PVLRE
2266
GVLTG
2271
SPEQK
2276
EEAAK
2281
ALGLV
2286
IRLTS
2291
ADALR
2296
PSVVS
2301
ITGPL
2306
IRILG
2311
DRFSW
2316
NVKAA
2321
LLETL
2326
SLLLA
2331
KVGIA
2336
LKPFL
2341
PQLQT
2346
TFTKA
2351
LQDSN
2356
RGVRL
2361
KAADA
2366
LGKLI
2371
SIHIK
2376
VDPLF
2381
TELLN
2386
GIRAM
2391
EDPGV
2396
RDTML
2401
QALRF
2406
VIQGA
2411
GAKVD
2416
AVIRK
2421
NIVSL
2426
LLSML
2431
GHDED
2436
NTRIS
2441
SAGCL
2446
GELCA
2451
FLTEE
2456
ELSAV
2461
LQQCL
2466
LADVS
2471
GIDWM
2476
VRHGR
2481
SLALS
2486
VAVNV
2491
APGRL
2496
CAGRY
2501
SSDVQ
2506
EMILS
2511
SATAD
2516
RIPIA
2521
VSGVR
2526
GMGFL
2531
MRHHI
2536
ETGGG
2541
QLPAK
2546
LSSLF
2551
VKCLQ
2556
NPSSD
2561
IRLVA
2566
EKMIW
2571
WANKD
2576
PLPPL
2581
DPQAI
2586
KPILK
2591
ALLDN
2596
TKDKN
2601
TVVRA
2606
YSDQA
2611
IVNLL
2616
KMRQG
2621
EEVFQ
2626
SLSKI
2631
LDVAS
2636
LEVLN
2641
EVNRR
2646
SLKKL
2651
ASQAD
2656
STEQV
2661
DDTIL
2666
T
2671
Mutation Information
DNA mutation:
None
Peptide Range:
2325 ~ 2334
Mut AA position:
2330 (6 in Wild Type peptide)
Alignment
Wild Type:
"ALLETLSLLL
|||||.||||
Mutant:
ALLETPSLLL"
reference
clinic trial
Checkpoint Blockade

None

ACT

N

Vaccination

N

Curative Effect

None

experiment
minimal_peptide

Y

Antigen Type

tetramer

T-cell Source

TILs

APC Type

None

Assay

None