Immunogenicity 15853

summary
Sample ID
patient1/P11-CDK4-R24L
Response
Positive
Tumor Type
Melanoma
Gene Symbol
CDK4 (FPKM: 3370000)
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

TRAJAJ47

CDR3ACALPYGNKLVF

TRBVBV12-4

TRBDBD2

TRBJBJ2-7

TRAVAV38-1

CDR3BCASTPTGAYEQYF

T cell Tumor cell A*02:01
sequence
Full length protein sequence (303 aa)
MATSR
1
YEPVA
6
EIGVG
11
AYGTV
16
YKARD
21
PHSGH
26
FVALK
31
SVRVP
36
NGGGG
41
GGGLP
46
ISTVR
51
EVALL
56
RRLEA
61
FEHPN
66
VVRLM
71
DVCAT
76
SRTDR
81
EIKVT
86
LVFEH
91
VDQDL
96
RTYLD
101
KAPPP
106
GLPAE
111
TIKDL
116
MRQFL
121
RGLDF
126
LHANC
131
IVHRD
136
LKPEN
141
ILVTS
146
GGTVK
151
LADFG
156
LARIY
161
SYQMA
166
LTPVV
171
VTLWY
176
RAPEV
181
LLQST
186
YATPV
191
DMWSV
196
GCIFA
201
EMFRR
206
KPLFC
211
GNSEA
216
DQLGK
221
IFDLI
226
GLPPE
231
DDWPR
236
DVSLP
241
RGAFP
246
PRGPR
251
PVQSV
256
VPEME
261
ESGAQ
266
LLLEM
271
LTFNP
276
HKRIS
281
AFRAL
286
QHSYL
291
HKDEG
296
NPE
301
Mutation Information
DNA mutation:
None
Peptide Range:
23 ~ 32
Mut AA position:
None (2 in Wild Type peptide)
Alignment
Wild Type:
"ARDPHSGHFV
|.||||||||
Mutant:
ALDPHSGHFV"
reference
clinic trial
Checkpoint Blockade

None

ACT

N

Vaccination

Y

Curative Effect

disease free

experiment
minimal_peptide

Y

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

MoDCs

Assay

None