Immunogenicity 1586

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SLC5A12
Transcript ID
ENST00000280467
HLA INFO
B*14:02
TCR INFO

No TCR info found!

T cell Tumor cell B*14:02
sequence
Full length protein sequence (396 aa)
MEVKN
1
FAVWD
6
YVVFA
11
ALFFI
16
SSGIG
21
VFFAI
26
KERKK
31
ATSRE
36
FLVGG
41
RQMSF
46
GPVGL
51
SLTAS
56
FMSAV
61
TVLGT
66
PSEVY
71
RFGAS
76
FLVFF
81
IAYLF
86
VILLT
91
SELFL
96
PVFYR
101
SGITS
106
TYEYL
111
QLRFN
116
KPVRY
121
AATVI
126
YIVQT
131
ILYTG
136
VVVYA
141
PALAL
146
NQVTG
151
FDLWG
156
SVFAT
161
GIVCT
166
FYCTL
171
GGLKA
176
VVWTD
181
AFQMV
186
VMIVG
191
FLTVL
196
IQGST
201
HAGGF
206
HNVLE
211
QSTNG
216
SRLHI
221
FDFDV
226
DPLRR
231
HTFWT
236
ITVGG
241
TFTWL
246
GIYGV
251
NQSTI
256
QRCIS
261
CKTEK
266
HAKLA
271
LYFNL
276
LGLWI
281
ILVCA
286
VFSGL
291
IMYSH
296
FKDCD
301
PWTSG
306
IISAP
311
DQLMP
316
YFVME
321
IFATM
326
PGLPG
331
LFVAC
336
AFSGT
341
LSTVA
346
SSINA
351
LATVT
356
FEDFV
361
KSCFP
366
HLSDK
371
LSTWI
376
SKGLC
381
RYSWW
386
TFYSI
391
S
396
Mutation Information
DNA mutation:
None
Peptide Range:
39 ~ 63
Mut AA position:
51 (13 in Wild Type peptide)
Alignment
Wild Type:
"REFLVGGRQMSFGPVGLSLTASFMS
||||||||||||.||||||||||||
Mutant:
REFLVGGRQMSFRPVGLSLTASFMS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SLC5A12

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay