Immunogenicity 15864

summary
Sample ID
None
Response
Positive
Tumor Type
Melanoma
Gene Symbol
ATR
Transcript ID
None
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (2646 aa)
MGEHG
1
LELAS
6
MIPAL
11
RELGS
16
ATPEE
21
YNTVV
26
QKPRQ
31
ILCQF
36
IDRIL
41
TDVNV
46
VAVEL
51
VKKTD
56
SQPTS
61
VMLLD
66
FIQHI
71
MKSSP
76
LMFVN
81
VSGSH
86
EAKGS
91
CIEFS
96
NWIIT
101
RLLRI
106
AATPS
111
CHLLH
116
KKICE
121
VICSL
126
LFLFK
131
SKSPA
136
IFGVL
141
TKELL
146
QLFED
151
LVYLH
156
RRNVM
161
GHAVE
166
WPVVM
171
SRFLS
176
QLDEH
181
MGYLQ
186
SAPLQ
191
LMSMQ
196
NLEFI
201
EVTLL
206
MVLTR
211
IIAIV
216
FFRRQ
221
ELLLW
226
QIGCV
231
LLEYG
236
SPKIK
241
SLAIS
246
FLTEL
251
FQLGG
256
LPAQP
261
ASTFF
266
SSFLE
271
LLKHL
276
VEMDT
281
DQLKL
286
YEEPL
291
SKLIK
296
TLFPF
301
EAEAY
306
RNIEP
311
VYLNM
316
LLEKL
321
CVMFE
326
DGVLM
331
RLKSD
336
LLKAA
341
LCHLL
346
QYFLK
351
FVPAG
356
YESAL
361
QVRKV
366
YVRNI
371
CKALL
376
DVLGI
381
EVDAE
386
YLLGP
391
LYAAL
396
KMESM
401
EIIEE
406
IQCQT
411
QQENL
416
SSNSD
421
GISPK
426
RRRLS
431
SSLNP
436
SKRAP
441
KQTEE
446
IKHVD
451
MNQKS
456
ILWSA
461
LKQKA
466
ESLQI
471
SLEYS
476
GLKNP
481
VIEML
486
EGIAV
491
VLQLT
496
ALCTV
501
HCSHQ
506
NMNCR
511
TFKDC
516
QHKSK
521
KKPSV
526
VITWM
531
SLDFY
536
TKVLK
541
SCRSL
546
LESVQ
551
KLDLE
556
ATIDK
561
VVKIY
566
DALIY
571
MQVNS
576
SFEDH
581
ILEDL
586
CGMLS
591
LPWIY
596
SHSDD
601
GCLKL
606
TTFAA
611
NLLTL
616
SCRIS
621
DSYSP
626
QAQSR
631
CVFLL
636
TLFPR
641
RIFLE
646
WRTAV
651
YNWAL
656
QSSHE
661
VIRAS
666
CVSGF
671
FILLQ
676
QQNSC
681
NRVPK
686
ILIDK
691
VKDDS
696
DIVKK
701
EFASI
706
LGQLV
711
CTLHG
716
MFYLT
721
SSLTE
726
PFSEH
731
GHVDL
736
FCRNL
741
KATSQ
746
HECSS
751
SQLKA
756
SVCKP
761
FLFLL
766
KKKIP
771
SPVKL
776
AFIDN
781
LHHLC
786
KHLDF
791
REDET
796
DVKAV
801
LGTLL
806
NLMED
811
PDKDV
816
RVAFS
821
GNIKH
826
ILESL
831
DSEDG
836
FIKEL
841
FVLRM
846
KEAYT
851
HAQIS
856
RNNEL
861
KDTLI
866
LTTGD
871
IGRAA
876
KGDLV
881
PFALL
886
HLLHC
891
LLSKS
896
ASVSG
901
AAYTE
906
IRALV
911
AAKSV
916
KLQSF
921
FSQYK
926
KPICQ
931
FLVES
936
LHSSQ
941
MTALP
946
NTPCQ
951
NADVR
956
KQDVA
961
HQREM
966
ALNTL
971
SEIAN
976
VFDFP
981
DLNRF
986
LTRTL
991
QVLLP
996
DLAAK
1001
ASPAA
1006
SALIR
1011
TLGKQ
1016
LNVNR
1021
REILI
1026
NNFKY
1031
IFSHL
1036
VCSCS
1041
KDELE
1046
RALHY
1051
LKNET
1056
EIELG
1061
SLLRQ
1066
DFQGL
1071
HNELL
1076
LRIGE
1081
HYQQV
1086
FNGLS
1091
ILASF
1096
ASSDD
1101
PYQGP
1106
RDIIS
1111
PELMA
1116
DYLQP
1121
KLLGI
1126
LAFFN
1131
MQLLS
1136
SSVGI
1141
EDKKM
1146
ALNSL
1151
MSLMK
1156
LMGPK
1161
HVSSV
1166
RVKMM
1171
TTLRT
1176
GLRFK
1181
DDFPE
1186
LCCRA
1191
WDCFV
1196
RCLDH
1201
ACLGS
1206
LLSHV
1211
IVALL
1216
PLIHI
1221
QPKET
1226
AAIFH
1231
YLIIE
1236
NRDAV
1241
QDFLH
1246
EIYFL
1251
PDHPE
1256
LKKIK
1261
AVLQE
1266
YRKET
1271
SESTD
1276
LQTTL
1281
QLSMK
1286
AIQHE
1291
NVDVR
1296
IHALT
1301
SLKET
1306
LYKNQ
1311
EKLIK
1316
YATDS
1321
ETVEP
1326
IISQL
1331
VTVLL
1336
KGCQD
1341
ANSQA
1346
RLLCG
1351
ECLGE
1356
LGAID
1361
PGRLD
1366
FSTTE
1371
TQGKD
1376
FTFVI
1381
ETGVE
1386
DSSFA
1391
YGLLM
1396
ELTRA
1401
YLAYA
1406
DNSRA
1411
QDSAA
1416
YAIQE
1421
LLSIY
1426
DCREM
1431
ETNGP
1436
GHQLW
1441
RRFPE
1446
HVREI
1451
LEPHL
1456
NTRYK
1461
SSQKS
1466
TDWSG
1471
VKKPI
1476
YLSKL
1481
GSNFA
1486
EWSAS
1491
WAGYL
1496
ITKVR
1501
HDLAS
1506
KIFTC
1511
CSIMM
1516
KHDFK
1521
VTIYL
1526
LPHIL
1531
VYVLL
1536
GCNQE
1541
DQQEV
1546
YAEIM
1551
AVLKH
1556
DDQHT
1561
INTQD
1566
IASDL
1571
CQLST
1576
QTVFS
1581
MLDHL
1586
TQWAR
1591
HKFQA
1596
LKAEK
1601
CPHSK
1606
SNRNK
1611
VDSMV
1616
STVDY
1621
EDYQS
1626
VTRFL
1631
DLIPQ
1636
DTLAV
1641
ASFRS
1646
KAYTR
1651
AVMHF
1656
ESFIT
1661
EKKQN
1666
IQEHL
1671
GFLQK
1676
LYAAM
1681
HEPDG
1686
VAGVS
1691
AIRKA
1696
EPSLK
1701
EQILE
1706
HESLG
1711
LLRDA
1716
TACYD
1721
RAIQL
1726
EPDQI
1731
IHYHG
1736
VVKSM
1741
LGLGQ
1746
LSTVI
1751
TQVNG
1756
VHANR
1761
SEWTD
1766
ELNTY
1771
RVEAA
1776
WKLSQ
1781
WDLVE
1786
NYLAA
1791
DGKST
1796
TWSVR
1801
LGQLL
1806
LSAKK
1811
RDITA
1816
FYDSL
1821
KLVRA
1826
EQIVP
1831
LSAAS
1836
FERGS
1841
YQRGY
1846
EYIVR
1851
LHMLC
1856
ELEHS
1861
IKPLF
1866
QHSPG
1871
DSSQE
1876
DSLNW
1881
VARLE
1886
MTQNS
1891
YRAKE
1896
PILAL
1901
RRALL
1906
SLNKR
1911
PDYNE
1916
MVGEC
1921
WLQSA
1926
RVARK
1931
AGHHQ
1936
TAYNA
1941
LLNAG
1946
ESRLA
1951
ELYVE
1956
RAKWL
1961
WSKGD
1966
VHQAL
1971
IVLQK
1976
GVELC
1981
FPENE
1986
TPPEG
1991
KNMLI
1996
HGRAM
2001
LLVGR
2006
FMEET
2011
ANFES
2016
NAIMK
2021
KYKDV
2026
TACLP
2031
EWEDG
2036
HFYLA
2041
KYYDK
2046
LMPMV
2051
TDNKM
2056
EKQGD
2061
LIRYI
2066
VLHFG
2071
RSLQY
2076
GNQFI
2081
YQSMP
2086
RMLTL
2091
WLDYG
2096
TKAYE
2101
WEKAG
2106
RSDRV
2111
QMRND
2116
LGKIN
2121
KVITE
2126
HTNYL
2131
APYQF
2136
LTAFS
2141
QLISR
2146
ICHSH
2151
DEVFV
2156
VLMEI
2161
IAKVF
2166
LAYPQ
2171
QAMWM
2176
MTAVS
2181
KSSYP
2186
MRVNR
2191
CKEIL
2196
NKAIH
2201
MKKSL
2206
EKFVG
2211
DATRL
2216
TDKLL
2221
ELCNK
2226
PVDGS
2231
SSTLS
2236
MSTHF
2241
KMLKK
2246
LVEEA
2251
TFSEI
2256
LIPLQ
2261
SVMIP
2266
TLPSI
2271
LGTHA
2276
NHASH
2281
EPFPG
2286
HWAYI
2291
AGFDD
2296
MVEIL
2301
ASLQK
2306
PKKIS
2311
LKGSD
2316
GKFYI
2321
MMCKP
2326
KDDLR
2331
KDCRL
2336
MEFNS
2341
LINKC
2346
LRKDA
2351
ESRRR
2356
ELHIR
2361
TYAVI
2366
PLNDE
2371
CGIIE
2376
WVNNT
2381
AGLRP
2386
ILTKL
2391
YKEKG
2396
VYMTG
2401
KELRQ
2406
CMLPK
2411
SAALS
2416
EKLKV
2421
FREFL
2426
LPRHP
2431
PIFHE
2436
WFLRT
2441
FPDPT
2446
SWYSS
2451
RSAYC
2456
RSTAV
2461
MSMVG
2466
YILGL
2471
GDRHG
2476
ENILF
2481
DSLTG
2486
ECVHV
2491
DFNCL
2496
FNKGE
2501
TFEVP
2506
EIVPF
2511
RLTHN
2516
MVNGM
2521
GPMGT
2526
EGLFR
2531
RACEV
2536
TMRLM
2541
RDQRE
2546
PLMSV
2551
LKTFL
2556
HDPLV
2561
EWSKP
2566
VKGHS
2571
KAPLN
2576
ETGEV
2581
VNEKA
2586
KTHVL
2591
DIEQR
2596
LQGVI
2601
KTRNR
2606
VTGLP
2611
LSIEG
2616
HVHYL
2621
IQEAT
2626
DENLL
2631
CQMYL
2636
GWTPY
2641
M
2646
Mutation Information
DNA mutation:
None
Peptide Range:
289 ~ 297
Mut AA position:
None (8 in Wild Type peptide)
Alignment
Wild Type:
"KLYEEPLSK
|||||||.|
Mutant:
KLYEEPLLK"
reference
clinic trial
Checkpoint Blockade

ipilimumab

ACT

N

Vaccination

N

Curative Effect

marked regression

experiment
minimal_peptide

Y

Antigen Type

minigene mRNA

T-cell Source

PBMCs

APC Type

MoDCs

Assay

None