Immunogenicity 159
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
SHROOM2
Transcript ID
uc011mic.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (451 aa)
METSR
1
SPSPQ
6
FAPQK
11
LTDKP
16
PLLIQ
21
DEDST
26
RIERV
31
MDNNT
36
TVKMV
41
PIKIV
46
HSESQ
51
PEKES
56
RQSLA
61
CPAEP
66
PALPH
71
GLEKD
76
QIKTL
81
STSEQ
86
FYSRF
91
CLYTR
96
QGAEP
101
EAPHR
106
AQPAE
111
PQPLG
116
TQVPP
121
EKDRC
126
TSPPG
131
LSYMK
136
AKEKT
141
VEDLK
146
SEELA
151
REIVG
156
KDKSL
161
ADILD
166
PSVKI
171
KTTMD
176
LMEGI
181
FPKDE
186
HLLEE
191
AQQRR
196
KLLPK
201
IPSPR
206
STEER
211
KEEPS
216
VPAAV
221
SLATN
226
STYYS
231
TSAPK
236
AELLI
241
KMKDL
246
QEQQE
251
HEEDS
256
GSDLD
261
HDLSV
266
KKQEL
271
IESIS
276
RKLQV
281
LREAR
286
ESLLE
291
DVQAN
296
TVLGA
301
EVEAI
306
VKGVC
311
KPSEF
316
DKFRM
321
FIGDL
326
DKVVN
331
LLLSL
336
SGRLA
341
RVENA
346
LNNLD
351
DGASP
356
GDRQS
361
LLEKQ
366
RVLIQ
371
QHEDA
376
KELKE
381
NLDRR
386
ERIVF
391
DILAN
396
YLSEE
401
SLADY
406
EHFVK
411
MKSAL
416
IIEQR
421
ELEDK
426
IHLGE
431
EQLKC
436
LLDSL
441
QPERG
446
K
451
Mutation Information
DNA mutation:
c.C571T
Peptide Range:
179 ~ 203
Mut AA position:
191 (13 in Wild Type peptide)
Alignment
Wild Type:
"MDLMEGIFPKDEHLLEEAQQRRKLL
||||||||||||.||||||||||||
Mutant:
MDLMEGIFPKDEYLLEEAQQRRKLL"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) SHROOM2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
MDLMEGIFPKDEYLLEEAQQRRKLL
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT