Immunogenicity 15907

summary
Sample ID
None
Response
Positive
Tumor Type
Gliomas
Gene Symbol
IDH1
Transcript ID
None
HLA INFO
DRB1*01:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB1*01:01
sequence
Full length protein sequence (414 aa)
MSKKI
1
SGGSV
6
VEMQG
11
DEMTR
16
IIWEL
21
IKEKL
26
IFPYV
31
ELDLH
36
SYDLG
41
IENRD
46
ATNDQ
51
VTKDA
56
AEAIK
61
KHNVG
66
VKCAT
71
ITPDE
76
KRVEE
81
FKLKQ
86
MWKSP
91
NGTIR
96
NILGG
101
TVFRE
106
AIICK
111
NIPRL
116
VSGWV
121
KPIII
126
GRHAY
131
GDQYR
136
ATDFV
141
VPGPG
146
KVEIT
151
YTPSD
156
GTQKV
161
TYLVH
166
NFEEG
171
GGVAM
176
GMYNQ
181
DKSIE
186
DFAHS
191
SFQMA
196
LSKGW
201
PLYLS
206
TKNTI
211
LKKYD
216
GRFKD
221
IFQEI
226
YDKQY
231
KSQFE
236
AQKIW
241
YEHRL
246
IDDMV
251
AQAMK
256
SEGGF
261
IWACK
266
NYDGD
271
VQSDS
276
VAQGY
281
GSLGM
286
MTSVL
291
VCPDG
296
KTVEA
301
EAAHG
306
TVTRH
311
YRMYQ
316
KGQET
321
STNPI
326
ASIFA
331
WTRGL
336
AHRAK
341
LDNNK
346
ELAFF
351
ANALE
356
EVSIE
361
TIEAG
366
FMTKD
371
LAACI
376
KGLPN
381
VQRSD
386
YLNTF
391
EFMDK
396
LGENL
401
KIKLA
406
QAKL
411
Mutation Information
DNA mutation:
None
Peptide Range:
123 ~ 142
Mut AA position:
132 (10 in Wild Type peptide)
Alignment
Wild Type:
"GWVKPIIIGRHAYGDQYRAT
|||||||||.||||||||||
Mutant:
GWVKPIIIGHHAYGDQYRAT"
reference

Nature, 2014

A vaccine targeting mutant IDH1 induces antitumour immunity

Gene Name (from Reference) IDH1

clinic trial
Checkpoint Blockade

None

ACT

N

Vaccination

N

Curative Effect

N

experiment
minimal_peptide

N

Antigen Type

peptide

T-cell Source

PBMCs

APC Type

T2

Assay

ELISPOT