Immunogenicity 1615
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
PRAG1
Transcript ID
ENST00000330777
HLA INFO
C*16:01
TCR INFO
No TCR info found!
Full length protein sequence (1402 aa)
MHQTL
1
CLNPE
6
SLKMS
11
ACSDF
16
VEHIW
21
KPGSC
26
KNCFC
31
LRSDH
36
QLVAG
41
PPQPR
46
AGSLP
51
PPPRL
56
PPRPE
61
NCRLE
66
DEGVN
71
SSPYS
76
KPTIA
81
VKPTM
86
MSSEA
91
SDVWT
96
EANLS
101
AEVSQ
106
VIWRR
111
APGKL
116
PLPKQ
121
EDAPV
126
VYLGS
131
FRGVQ
136
KPAGP
141
STSPD
146
GNSRC
151
PPAYT
156
MVGLH
161
NLEPR
166
GERNI
171
AFHPV
176
SFPEE
181
KAVHK
186
EKPSF
191
PYQDR
196
PSTQE
201
SFRQK
206
LAAFA
211
GTTSG
216
CHQGP
221
GPLRE
226
SLPSE
231
DDSDQ
236
RCSPS
241
GDSEG
246
GEYCS
251
ILDCC
256
PGSPV
261
AKAAS
266
QTAGS
271
RGRHG
276
GRDCS
281
PTCWE
286
QGKCS
291
GPAEQ
296
EKRGP
301
SFPKE
306
CCSQG
311
PTAHP
316
SCLGP
321
KKLSL
326
TSEAA
331
ISSDG
336
LSCGS
341
GSGSG
346
ASSPF
351
VPHLE
356
SDYCS
361
LMKEP
366
APEKQ
371
QDPGC
376
PGVTP
381
SRCLG
386
LTGEP
391
QPPAH
396
PREAT
401
QPEPI
406
YAEST
411
KRKKA
416
APVPS
421
KSQAK
426
IEHAA
431
AAQGQ
436
GQVCT
441
GNAWA
446
QKAAS
451
GWGRD
456
SPDPT
461
PQVSA
466
TITVM
471
AAHPE
476
EDHRT
481
IYLSS
486
PDSAV
491
GVQWP
496
RGPVS
501
QNSEV
506
GEEET
511
SAGQG
516
LSSRE
521
SHAHS
526
ASESK
531
PKERP
536
AIPPK
541
LSKSS
546
PVGSP
551
VSPSA
556
GGPPV
561
SPLAD
566
LSDGS
571
SGGSS
576
IGPQP
581
PSQGP
586
ADPAP
591
SCRTN
596
GVAIS
601
DPSRC
606
PQPAA
611
SSASE
616
QRRPR
621
FQAGT
626
WSRQC
631
RIEEE
636
EEVEQ
641
ELLSH
646
SWGRE
651
TKNGP
656
TDHSN
661
STTWH
666
RLHPT
671
DGSSG
676
QNSKV
681
GTGMS
686
KSASF
691
AFEFP
696
KDRSG
701
IETFS
706
PPPPP
711
PKSRH
716
LLKMN
721
KSSSD
726
LEKVS
731
QGSAE
736
SLSPS
741
FRGVH
746
VSFTT
751
GSTDS
756
LASDS
761
RTCSD
766
GGPSS
771
ELAHS
776
PTNSG
781
KKLFA
786
PVPFP
791
SGSTE
796
DVSPS
801
GPQQP
806
PPLPQ
811
KKIVS
816
RAASS
821
PDGFF
826
WTQGS
831
PKPGT
836
ASPKL
841
NLSHS
846
ETNVH
851
DESHF
856
SYSLS
861
PGNRH
866
HPVFS
871
SSDPL
876
EKAFK
881
GSGHW
886
LPAAG
891
LAGNR
896
GGCGS
901
PGLQC
906
KGAPS
911
ASSSQ
916
LSVSS
921
QASTG
926
STQLQ
931
LHGLL
936
SNISS
941
KEGTY
946
AKLGG
951
LYTQS
956
LARLV
961
AKCED
966
LFMGG
971
QKKEL
976
HFNEN
981
NWSLF
986
KLTCN
991
KPCCD
996
SGDAI
1001
YYCAT
1006
CSEDP
1011
GSTYA
1016
VKICK
1021
APEPK
1026
TVSYC
1031
SPSVP
1036
VHFNI
1041
QQDCG
1046
HFVAS
1051
VPSSM
1056
LSSPD
1061
APKDP
1066
VPALP
1071
THPPA
1076
QEQDC
1081
VVVIT
1086
REVPH
1091
QTASD
1096
FVRDS
1101
AASHQ
1106
AEPEA
1111
YERRV
1116
CFLLL
1121
QLCNG
1126
LEHLK
1131
EHGII
1136
HRDLC
1141
LENLL
1146
LVHCT
1151
LQAGP
1156
GPAPA
1161
PAPAP
1166
AAAAP
1171
PCSSA
1176
APPAG
1181
GTLSP
1186
AAGPA
1191
SPEGP
1196
REKQL
1201
PRLII
1206
SNFLK
1211
AKQKP
1216
GGTPN
1221
LQQKK
1226
SQARL
1231
APEIV
1236
SASQY
1241
RKFDE
1246
FQTGI
1251
LIYEL
1256
LHQPN
1261
PFEVR
1266
AQLRE
1271
RDYRQ
1276
EDLPP
1281
LPALS
1286
LYSPG
1291
LQQLA
1296
HLLLE
1301
ADPIK
1306
RIRIG
1311
EAKRV
1316
LQCLL
1321
WGPRR
1326
ELVQQ
1331
PGTSE
1336
EALCG
1341
TLHNW
1346
IDMKR
1351
ALMMM
1356
KFAEK
1361
AVDRR
1366
RGVEL
1371
EDWLC
1376
CQYLA
1381
SAEPG
1386
ALLQS
1391
LKLLQ
1396
LL
1401
Mutation Information
DNA mutation:
None
Peptide Range:
442 ~ 466
Mut AA position:
454 (13 in Wild Type peptide)
Alignment
Wild Type:
"QVCTGNAWAQKAASGWGRDSPDPTP
||||||||||||.||||||||||||
Mutant:
QVCTGNAWAQKAVSGWGRDSPDPTP"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) SGK223
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay