Immunogenicity 1627

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
LRP4
Transcript ID
ENST00000546834
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (556 aa)
MLLAT
1
LLLLL
6
LGGAL
11
AHPDR
16
IIFPN
21
HACED
26
PPAVL
31
LEVQG
36
TLQRP
41
LVRDS
46
RTSPA
51
NCTWL
56
ILGSK
61
EQTVT
66
IRFQK
71
LHLAC
76
GSERL
81
TLRSP
86
LQPLI
91
SLCEA
96
PPSPL
101
QLPGG
106
NVTIT
111
YSYAG
116
ARAPM
121
GQGFL
126
LSYSQ
131
DWLMC
136
LQEEF
141
QCLNH
146
RCVSA
151
VQRCD
156
GVDAC
161
GDGSD
166
EAGCS
171
SDPFP
176
GLTPR
181
PVPSL
186
PCNVT
191
LEDFY
196
GVFSS
201
PGYTH
206
LASVS
211
HPQSC
216
HWLLD
221
PHDGR
226
RLAVR
231
FTALD
236
LGFGD
241
AVHVY
246
DGPGP
251
PESSR
256
LLRSL
261
THFSN
266
GKAVT
271
VETLS
276
GQAVV
281
SYHTV
286
AWSNG
291
RGFNA
296
TYHVR
301
GYCLP
306
WDRPC
311
GLGSG
316
LGAGE
321
GLGER
326
CYSEA
331
QRCDG
336
SWDCA
341
DGTDE
346
EDCPG
351
CPPGH
356
FPCGA
361
AGTSG
366
ATACY
371
LPADR
376
CNYQT
381
FCADG
386
ADERR
391
CRHCQ
396
PGNFR
401
CRDEK
406
CVYET
411
WVCDG
416
QPDCA
421
DGSDE
426
WDCSY
431
VLPRK
436
VITAA
441
VIGSL
446
VCGLL
451
LVIAL
456
GCTCK
461
LYAIR
466
TQEYS
471
IFAPL
476
SRMEA
481
EIVQQ
486
QAPPS
491
YGQLI
496
AQGAI
501
PPVED
506
FPTEN
511
PNDNS
516
VLGNL
521
RSLLQ
526
ILRQD
531
MTPGG
536
GPGAR
541
RRQRG
546
RLMRR
551
L
556
Mutation Information
DNA mutation:
None
Peptide Range:
194 ~ 218
Mut AA position:
206 (13 in Wild Type peptide)
Alignment
Wild Type:
"VTLEDFYGVFSSPGYTHLASVSHPQ
||||||||||||.||||||||||||
Mutant:
VTLEDFYGVFSSLGYTHLASVSHPQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) LRP10

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay