Immunogenicity 1653

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CNTN1
Transcript ID
ENST00000348761
HLA INFO
DRB*13:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*13:01
sequence
Full length protein sequence (1007 aa)
MKMWL
1
LVSHL
6
VIISI
11
TTCLA
16
VSEED
21
KGFGP
26
IFEEQ
31
PINTI
36
YPEES
41
LEGKV
46
SLNCR
51
ARASP
56
FPVYK
61
WRMNN
66
GDVDL
71
TSDRY
76
SMVGG
81
NLVIN
86
NPDKQ
91
KDAGI
96
YYCLA
101
SNNYG
106
MVRST
111
EATLS
116
FGYLD
121
PFPPE
126
ERPEV
131
RVKEG
136
KGMVL
141
LCDPP
146
YHFPD
151
DLSYR
156
WLLNE
161
FPVFI
166
TMDKR
171
RFVSQ
176
TNGNL
181
YIANV
186
EASDK
191
GNYSC
196
FVSSP
201
SITKS
206
VFSKF
211
IPLIP
216
IPERT
221
TKPYP
226
ADIVV
231
QFKDV
236
YALMG
241
QNVTL
246
ECFAL
251
GNPVP
256
DIRWR
261
KVLEP
266
MPSTA
271
EISTS
276
GAVLK
281
IFNIQ
286
LEDEG
291
IYECE
296
AENIR
301
GKDKH
306
QARIY
311
VQAFP
316
EWVEH
321
INDTE
326
VDIGS
331
DLYWP
336
CVATG
341
KPIPT
346
IRWLK
351
NGYAY
356
HKGEL
361
RLYDV
366
TFENA
371
GMYQC
376
IAENT
381
YGAIY
386
ANAEL
391
KILAL
396
APTFE
401
MNPMK
406
KKILA
411
AKGGR
416
VIIEC
421
KPKAA
426
PKPKF
431
SWSKG
436
TEWLV
441
NSSRI
446
LIWED
451
GSLEI
456
NNITR
461
NDGGI
466
YTCFA
471
ENNRG
476
KANST
481
GTLVI
486
TDPTR
491
IILAP
496
INADI
501
TVGEN
506
ATMQC
511
AASFD
516
PALDL
521
TFVWS
526
FNGYV
531
IDFNK
536
ENIHY
541
QRNFM
546
LDSNG
551
ELLIR
556
NAQLK
561
HAGRY
566
TCTAQ
571
TIVDN
576
SSASA
581
DLVVR
586
GPPGP
591
PGGLR
596
IEDIR
601
ATSVA
606
LTWSR
611
GSDNH
616
SPISK
621
YTIQT
626
KTILS
631
DDWKD
636
AKTDP
641
PIIEG
646
NMEAA
651
RAVDL
656
IPWME
661
YEFRV
666
VATNT
671
LGRGE
676
PSIPS
681
NRIKT
686
DGAAP
691
NVAPS
696
DVGGG
701
GGRNR
706
ELTIT
711
WAPLS
716
REYHY
721
GNNFG
726
YIVAF
731
KPFDG
736
EEWKK
741
VTVTN
746
PDTGR
751
YVHKD
756
ETMSP
761
STAFQ
766
VKVKA
771
FNNKG
776
DGPYS
781
LVAVI
786
NSAQD
791
APSEA
796
PTEVG
801
VKVLS
806
SSEIS
811
VHWEH
816
VLEKI
821
VESYQ
826
IRYWA
831
AHDKE
836
EAANR
841
VQVTS
846
QEYSA
851
RLENL
856
LPDTQ
861
YFIEV
866
GACNS
871
AGCGP
876
PSDMI
881
EAFTK
886
KAPPS
891
QPPRI
896
ISSVR
901
SGSRY
906
IITWD
911
HVVAL
916
SNEST
921
VTGYK
926
VLYRP
931
DGQHD
936
GKLYS
941
THKHS
946
IEVPI
951
PRDGE
956
YVVEV
961
RAHSD
966
GGDGV
971
VSQVK
976
ISGAP
981
TLSPS
986
LLGLL
991
LPAFG
996
ILVYL
1001
EF
1006
Mutation Information
DNA mutation:
None
Peptide Range:
199 ~ 223
Mut AA position:
211 (13 in Wild Type peptide)
Alignment
Wild Type:
"SCFVSSPSITKSVFSKFIPLIPIPE
||||||||||||.||||||||||||
Mutant:
SCFVSSPSITKSMFSKFIPLIPIPE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CNTN1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay