Immunogenicity 1663

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
POU1F1
Transcript ID
ENST00000344265
HLA INFO
DQA*02:01 / DQB*02:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*02:01 DQB*02:02
sequence
Full length protein sequence (317 aa)
MSCQA
1
FTSAD
6
TFIPL
11
NSDAS
16
ATLPL
21
IMHHS
26
AAECL
31
PVSNH
36
ATNVM
41
STVPS
46
ILSLI
51
QTPKC
56
LCTHF
61
SVTTL
66
GNTAT
71
GLHYS
76
VPSCH
81
YGNQP
86
STYGV
91
MAGSL
96
TPCLY
101
KFPDH
106
TLSHG
111
FPPIH
116
QPLLA
121
EDPTA
126
ADFKQ
131
ELRRK
136
SKLVE
141
EPIDM
146
DSPEI
151
RELEK
156
FANEF
161
KVRRI
166
KLGYT
171
QTNVG
176
EALAA
181
VHGSE
186
FSQTT
191
ICRFE
196
NLQLS
201
FKNAC
206
KLKAI
211
LSKWL
216
EEAEQ
221
VGALY
226
NEKVG
231
ANERK
236
RKRRT
241
TISIA
246
AKDAL
251
ERHFG
256
EQNKP
261
SSQEI
266
MRMAE
271
ELNLE
276
KEVVR
281
VWFCN
286
RRQRE
291
KRVKT
296
SLNQS
301
LFSIS
306
KEHLE
311
CR
316
Mutation Information
DNA mutation:
None
Peptide Range:
150 ~ 174
Mut AA position:
162 (13 in Wild Type peptide)
Alignment
Wild Type:
"MDSPEIRELEKFANEFKVRRIKLGY
||||||||||||.||||||||||||
Mutant:
MDSPEIRELEKFGNEFKVRRIKLGY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) POU1F1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay