Immunogenicity 1686
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
KARS
Transcript ID
ENST00000319410
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (625 aa)
MLTQA
1
AVRLV
6
RGSLR
11
KTSWA
16
EWGHR
21
ELRLG
26
QLAPF
31
TAPHK
36
DKSFS
41
DQRSE
46
LKRRL
51
KAEKK
56
VAEKE
61
AKQKE
66
LSEKQ
71
LSQAT
76
AAATN
81
HTTDN
86
GVGPE
91
EESVD
96
PNQYY
101
KIRSQ
106
AIHQL
111
KVNGE
116
DPYPH
121
KFHVD
126
ISLTD
131
FIQKY
136
SHLQP
141
GDHLT
146
DITLK
151
VAGRI
156
HAKRA
161
SGGKL
166
IFYDL
171
RGEGV
176
KLQVM
181
ANSRN
186
YKSEE
191
EFIHI
196
NNKLR
201
RGDII
206
GVQGN
211
PGKTK
216
KGELS
221
IIPYE
226
ITLLS
231
PCLHM
236
LPHLH
241
FGLKD
246
KETRY
251
RQRYL
256
DLILN
261
DFVRQ
266
KFIIR
271
SKIIT
276
YIRSF
281
LDELG
286
FLEIE
291
TPMMN
296
IIPGG
301
AVAKP
306
FITYH
311
NELDM
316
NLYMR
321
IAPEL
326
YHKML
331
VVGGI
336
DRVYE
341
IGRQF
346
RNEGI
351
DLTHN
356
PEFTT
361
CEFYM
366
AYADY
371
HDLME
376
ITEKM
381
VSGMV
386
KHITG
391
SYKVT
396
YHPDG
401
PEGQA
406
YDVDF
411
TPPFR
416
RINMV
421
EELEK
426
ALGMK
431
LPETN
436
LFETE
441
ETRKI
446
LDDIC
451
VAKAV
456
ECPPP
461
RTTAR
466
LLDKL
471
VGEFL
476
EVTCI
481
NPTFI
486
CDHPQ
491
IMSPL
496
AKWHR
501
SKEGL
506
TERFE
511
LFVMK
516
KEICN
521
AYTEL
526
NDPMR
531
QRQLF
536
EEQAK
541
AKAAG
546
DDEAM
551
FIDEN
556
FCTAL
561
EYGLP
566
PTAGW
571
GMGID
576
RVAMF
581
LTDSN
586
NIKEV
591
LLFPA
596
MKPED
601
KKENV
606
ATTDT
611
LESTT
616
VGTSV
621
Mutation Information
DNA mutation:
None
Peptide Range:
344 ~ 368
Mut AA position:
356 (13 in Wild Type peptide)
Alignment
Wild Type:
"YEIGRQFRNEGIDLTHNPEFTTCEF
||||||||||||.||||||||||||
Mutant:
YEIGRQFRNEGIHLTHNPEFTTCEF"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) KARS
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay