Immunogenicity 1693

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF700
Transcript ID
ENST00000482090
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (724 aa)
MFQDP
1
VAFED
6
VAVNF
11
TQEEW
16
TLLDI
21
SQKNL
26
FREVM
31
LETFR
36
NLTSI
41
GKKWS
46
DQNIE
51
YEYQN
56
PRRSF
61
RSLIE
66
EKVNE
71
IKEDS
76
HCGET
81
FTQVP
86
DDRLN
91
FQEKK
96
ASPEV
101
KSCDS
106
FVCAE
111
VGIGN
116
SSFNM
121
SIRGD
126
TGHKA
131
YEYQE
136
YGPKP
141
YKCQQ
146
PKNKK
151
AFRYR
156
PSIRT
161
QERDH
166
TGEKP
171
YACKV
176
CGKTF
181
IFHSS
186
IRRHM
191
VMHSG
196
DGTYK
201
CKFCG
206
KAFHS
211
FSLYL
216
IHERT
221
HTGEK
226
PYECK
231
QCGKS
236
FTYSA
241
TLQIH
246
ERTHT
251
GEKPY
256
ECSKC
261
DKAFH
266
SSSSY
271
HRHER
276
SHMGE
281
KPYQC
286
KECGK
291
AFAYT
296
SSLRR
301
HERTH
306
SGKKP
311
YECKQ
316
YGEGL
321
SYLIS
326
FQTHI
331
RMNSG
336
ERPYK
341
CKICG
346
KGFYS
351
AKSFQ
356
THEKT
361
HTGEK
366
RYKCK
371
QCGKA
376
FNLSS
381
SFRYH
386
ERIHT
391
GEKPY
396
ECKQC
401
GKAFR
406
SASQL
411
RVHGG
416
THTGE
421
KPYEC
426
KECGK
431
AFRST
436
SHLRV
441
HGRTH
446
TGEKP
451
YECKE
456
CGKAF
461
RYVKH
466
LQIHE
471
RTEKH
476
IRMPS
481
GERPY
486
KCSIC
491
EKGFY
496
SAKSF
501
QTHEK
506
THTGE
511
KPYEC
516
NQCGK
521
AFRCC
526
NSLRY
531
HERTH
536
TGEKP
541
YECKQ
546
CGKAF
551
RSASH
556
LRMHE
561
RTHTG
566
EKPYE
571
CKQCG
576
KAFSC
581
ASNLR
586
KHGRT
591
HTGEK
596
PYECK
601
QCGKA
606
FRSAS
611
NLQMH
616
ERTHT
621
GEKPY
626
ECKEC
631
EKAFC
636
KFSSF
641
QIHER
646
KHRGE
651
KPYEC
656
KHCGN
661
GFTSA
666
KILQI
671
HARTH
676
IGEKH
681
YECKE
686
CGKAF
691
NYFSS
696
LHIHA
701
RTHMG
706
EKPYE
711
CKDCG
716
KAFS
721
Mutation Information
DNA mutation:
None
Peptide Range:
501 ~ 525
Mut AA position:
513 (13 in Wild Type peptide)
Alignment
Wild Type:
"SAKSFQTHEKTHTGEKPYECNQCGK
||||||||||||.||||||||||||
Mutant:
SAKSFQTHEKTHSGEKPYECNQCGK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF700

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay