Immunogenicity 1725

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
ZNF433
Transcript ID
ENST00000344980
HLA INFO
DRB*03:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*03:01
sequence
Full length protein sequence (673 aa)
MMFQD
1
SVAFE
6
DVAVT
11
FTQEE
16
WALLD
21
PSQKN
26
LCRDV
31
MQETF
36
RNLAS
41
IGKKW
46
KPQNI
51
YVEYE
56
NLRRN
61
LRIVG
66
ERLFE
71
SKEGH
76
QHGEI
81
LTQVP
86
DDMLK
91
KTTTG
96
VKSCE
101
SSVYG
106
EVGSA
111
HSSLN
116
RHIRD
121
DTGHK
126
AYEYQ
131
EYGQK
136
PYKCK
141
YCKKP
146
FNCLS
151
SVQTH
156
ERAHS
161
GRKLY
166
VCEEC
171
GKTFI
176
SHSNL
181
QRHRI
186
MHRGD
191
GPYKC
196
KFCGK
201
ALMFL
206
SLYLI
211
HKRTH
216
TGEKP
221
YQCKQ
226
CGKAF
231
SHSSS
236
LRIHE
241
RTHTG
246
EKPYK
251
CNECG
256
KAFHS
261
STCLH
266
AHKRT
271
HTGEK
276
PYECK
281
QCGKA
286
FSSSH
291
SFQIH
296
ERTHT
301
GEKPY
306
ECKEC
311
GKAFK
316
CPSSV
321
RRHER
326
THSRK
331
KPYEC
336
KHCGK
341
VLSYL
346
TSFQN
351
HLGMH
356
TGEIS
361
HKCKI
366
CGKAF
371
YSPSS
376
LQTHE
381
KTHTG
386
EKPYK
391
CNQCG
396
KAFNS
401
SSSFR
406
YHERT
411
HTGEK
416
PYECK
421
QCGKA
426
FRSAS
431
LLQTH
436
GRTHT
441
GEKPY
446
ACKEC
451
GKPFS
456
NFSFF
461
QIHER
466
MHREE
471
KPYEC
476
KGYGK
481
TFSLP
486
SLFHR
491
HERTH
496
TGGKT
501
YECKQ
506
CGRSF
511
NCSSS
516
FRYHG
521
RTHTG
526
EKPYE
531
CKQCG
536
KAFRS
541
ASQLQ
546
IHGRT
551
HTGEK
556
PYECK
561
QCGKA
566
FGSAS
571
HLQMH
576
GRTHT
581
GEKPY
586
ECKQC
591
GKSFG
596
CASRL
601
QMHGR
606
THTGE
611
KPYKC
616
KQCGK
621
AFGCP
626
SNLRR
631
HGRTH
636
TGEKP
641
YKCNQ
646
CGKVF
651
RCSSQ
656
LQVHG
661
RAHCI
666
DTP
671
Mutation Information
DNA mutation:
None
Peptide Range:
205 ~ 229
Mut AA position:
217 (13 in Wild Type peptide)
Alignment
Wild Type:
"KALMFLSLYLIHKRTHTGEKPYQCK
||||||||||||.||||||||||||
Mutant:
KALMFLSLYLIHTRTHTGEKPYQCK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ZNF433

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay