Immunogenicity 174
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TACC2
Transcript ID
uc010qtv.2
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (2991 aa)
MGNEN
1
STSDN
6
QRTLS
11
AQTPR
16
SAQPP
21
GNSQN
26
IKRKQ
31
QDTPG
36
SPDHR
41
DASSI
46
GSVGL
51
GGFCT
56
ASESS
61
ASLDP
66
CLVSP
71
EVTEP
76
RKDPQ
81
GARGP
86
EGSLL
91
PSPPP
96
SQERE
101
HPSSS
106
MPFAE
111
CPPEG
116
CLASP
121
AAAPE
126
DGPQT
131
QSPRR
136
EPAPN
141
APGDI
146
AAAFP
151
AERDS
156
STPYQ
161
EIAAV
166
PSAGR
171
ERQPK
176
EEGQK
181
SSFSF
186
SSGID
191
QSPGM
196
SPVPL
201
REPMK
206
APLCG
211
EGDQP
216
GGFES
221
QEKEA
226
AGGFP
231
PAESR
236
QGVAS
241
VQVTP
246
EAPAA
251
AQQGT
256
ESSAV
261
LEKSP
266
LKPMA
271
PIPQD
276
PAPRA
281
SDRER
286
GQGEA
291
PPQYL
296
TDDLE
301
FLRAC
306
HLPRS
311
NSGAA
316
PEAEV
321
NAASQ
326
ESCQQ
331
PVGAY
336
LPHAE
341
LPWGL
346
PSPAL
351
VPEAG
356
GSGKE
361
ALDTI
366
DVQGH
371
PQTGM
376
RGTKP
381
NQVVC
386
VAAGG
391
QPEGG
396
LPVSP
401
EPSLL
406
TPTEE
411
AHPAS
416
SLASF
421
PAAQI
426
PIAVE
431
EPGSS
436
SRESV
441
SKAGM
446
PVSAD
451
AAKEV
456
VDAGL
461
VGLER
466
QVSDL
471
GSKGE
476
HPEGD
481
PGEVP
486
APSPQ
491
ERGEH
496
LNTEQ
501
SHEVQ
506
PGVPP
511
PPLPK
516
EQSHE
521
VQPGA
526
PPPPL
531
PKAPS
536
ESARG
541
PPGPT
546
DGAKV
551
HEDST
556
SPAVA
561
KEGSR
566
SPGDS
571
PGGKE
576
EAPEP
581
PDGGD
586
PGNLQ
591
GEDSQ
596
AFSSK
601
RDPEV
606
GKDEL
611
SKPSS
616
DAESR
621
DHPSS
626
HSAQP
631
PRKGG
636
AGHTD
641
GPHSQ
646
TAEAD
651
ASGLP
656
HKLGE
661
EDPVL
666
PPVPD
671
GAGEP
676
TVPEG
681
AIWEG
686
SGLQP
691
KCPDT
696
LQSRE
701
GLGRM
706
ESFLT
711
LESEK
716
SDFPP
721
TPVAE
726
VAPKA
731
QEGES
736
TLEIR
741
KMGSC
746
DGEGL
751
LTSPD
756
QPRGP
761
ACDAS
766
RQEFH
771
AGVPH
776
PPQGE
781
NLAAD
786
LGLTA
791
LILDQ
796
DQQGI
801
PSCPG
806
EGWIR
811
GAASE
816
WPLLS
821
SEKHL
826
QPSQA
831
QPETS
836
IFDVL
841
KEQAQ
846
PPENG
851
KETSP
856
SHPGF
861
KDQGA
866
DSSQI
871
HVPVE
876
PQEDN
881
NLPTH
886
GGQEQ
891
ALGSE
896
LQSQL
901
PKGTL
906
SDTPT
911
SSPTD
916
MVWES
921
SLTEE
926
SELSA
931
PTRQK
936
LPALG
941
EKRPE
946
GACGD
951
GQSSR
956
VSPPA
961
ADVLK
966
DFSLA
971
GNFSR
976
KETCC
981
TGQGP
986
NKSQQ
991
ALADA
996
LEEGS
1001
QHEEA
1006
CQRHP
1011
GASEA
1016
ADGCS
1021
PLWGL
1026
SKREM
1031
ASGNT
1036
GEAPP
1041
CQPDS
1046
VALLD
1051
AVPCL
1056
PALAP
1061
ASPGV
1066
TPTQD
1071
APETE
1076
ACDET
1081
QEGRQ
1086
QPVPA
1091
PQQKM
1096
ECWAT
1101
SDAES
1106
PKLLA
1111
SFPSA
1116
GEQGG
1121
EAGAA
1126
ETGGS
1131
AGAGD
1136
PGKQQ
1141
APEKP
1146
GEATL
1151
SCGLL
1156
QTEHC
1161
LTSGE
1166
EASTS
1171
ALRES
1176
CQAEH
1181
PMASC
1186
QDALL
1191
PAREL
1196
GGIPR
1201
STMDF
1206
STHQA
1211
VPDPK
1216
ELLLS
1221
GPPEV
1226
AAPDT
1231
PYLHV
1236
DSAAQ
1241
RGAED
1246
SGVKA
1251
VSSAD
1256
PRAPG
1261
ESPCP
1266
VGEPP
1271
LALEN
1276
AASLK
1281
LFAGS
1286
LAPLL
1291
QPGAA
1296
GGEIP
1301
AVQAS
1306
SGSPK
1311
ARTTE
1316
GPVDS
1321
MPCLD
1326
RMPLL
1331
AKGKQ
1336
ATGEE
1341
KAATA
1346
PGAGA
1351
KASGE
1356
GMAGD
1361
AAGET
1366
EGSME
1371
RMGEP
1376
SQDPK
1381
QGTSG
1386
GVDTS
1391
SEQIA
1396
TLTGF
1401
PDFRE
1406
HIAKI
1411
FEKPV
1416
LGALA
1421
TPGEK
1426
AGAGR
1431
SAVGK
1436
DLTRP
1441
LGPEK
1446
LLDGP
1451
PGVDV
1456
TLLPA
1461
PPARL
1466
QVEKK
1471
QQLAG
1476
EAEIS
1481
HLALQ
1486
DPASD
1491
KLLGP
1496
AGLTW
1501
ERNLP
1506
GAGVG
1511
KEMAG
1516
VPPTL
1521
REDER
1526
PEGPG
1531
AAWPG
1536
LEGQA
1541
YSQLE
1546
RSRQE
1551
LASGL
1556
PSPAA
1561
TQELP
1566
VERAA
1571
AFQVA
1576
PHSHG
1581
EEAVA
1586
QDRIP
1591
SGKQH
1596
QETSA
1601
CDSPH
1606
GEDGP
1611
GDFAH
1616
TGVPG
1621
HVPRS
1626
TCAPS
1631
PQREV
1636
LTVPE
1641
ANSEP
1646
WTLDT
1651
LGGER
1656
RPGVT
1661
AGILE
1666
MRNAL
1671
GNQST
1676
PAPPT
1681
GEVAD
1686
TPLEP
1691
GKVAG
1696
AAGEA
1701
EGDIT
1706
LSTAE
1711
TQACA
1716
SGDLP
1721
EAGTT
1726
RTFSV
1731
VAGDL
1736
VLPGS
1741
CQDPA
1746
CSDKA
1751
PGMEG
1756
TAALH
1761
GDSPA
1766
RPQQA
1771
KEQPG
1776
PERPI
1781
PAGDG
1786
KVCVS
1791
SPPEP
1796
DETHD
1801
PKLQH
1806
LAPEE
1811
LHTDR
1816
ESPRP
1821
GPSML
1826
PSVPK
1831
KDAPR
1836
VMDKV
1841
TSDET
1846
RGAEG
1851
TESSP
1856
VADDI
1861
IQPAA
1866
PADLE
1871
SPTLA
1876
ASSYH
1881
GDVVG
1886
QVSTD
1891
LIAQS
1896
ISPAA
1901
AHAGL
1906
PPSAA
1911
EHIVS
1916
PSAPA
1921
GDRVE
1926
ASTPS
1931
CPDPA
1936
KDLSR
1941
SSDSE
1946
EAFET
1951
PESTT
1956
PVKAP
1961
PAPPP
1966
PPPEV
1971
IPEPE
1976
VSTQP
1981
PPEEP
1986
GCGSE
1991
TVPVP
1996
DGPRS
2001
DSVEG
2006
SPFRP
2011
PSHSF
2016
SAVFD
2021
EDKPI
2026
ASSGT
2031
YNLDF
2036
DNIEL
2041
VDTFQ
2046
TLEPR
2051
ASDAK
2056
NQEGK
2061
VNTRR
2066
KSTDS
2071
VPISK
2076
STLSR
2081
SLSLQ
2086
ASDFD
2091
GASSS
2096
GNPEA
2101
VALAP
2106
DAYST
2111
GSSSA
2116
SSTLK
2121
RTKKP
2126
RPPSL
2131
KKKQT
2136
TKKPT
2141
ETPPV
2146
KETQQ
2151
EPDEE
2156
SLVPS
2161
GENLA
2166
SETKT
2171
ESAKT
2176
EGPSP
2181
ALLEE
2186
TPLEP
2191
AVGPK
2196
AACPL
2201
DSESA
2206
EGVVP
2211
PASGG
2216
GRVQN
2221
SPPVG
2226
RKTLP
2231
LTTAP
2236
EAGEV
2241
TPSDS
2246
GGQED
2251
SPAKG
2256
LSVRL
2261
EFDYS
2266
EDKSS
2271
WDNQQ
2276
ENPPP
2281
TKKIG
2286
KKPVA
2291
KMPLR
2296
RPKMK
2301
KTPEK
2306
LDNTP
2311
ASPPR
2316
SPAEP
2321
NDIPI
2326
AKGTY
2331
TFDID
2336
KWDDP
2341
NFNPF
2346
SSTSK
2351
MQESP
2356
KLPQQ
2361
SYNFD
2366
PDTCD
2371
ESVDP
2376
FKTSS
2381
KTPSS
2386
PSKSP
2391
ASFEI
2396
PASAM
2401
EANGV
2406
DGDGL
2411
NKPAK
2416
KKKTP
2421
LKTMV
2426
EDVMS
2431
VCSLF
2436
DTFRV
2441
KKSPK
2446
RSPLS
2451
DPPSQ
2456
DPTPA
2461
ATPET
2466
PPVIS
2471
AVVHA
2476
TDEEK
2481
LAVTN
2486
QKWTC
2491
MTVDL
2496
EADKQ
2501
DYPQP
2506
SDLST
2511
FVNET
2516
KFSSP
2521
TEGKQ
2526
LCSQL
2531
DPHSA
2536
SENPA
2541
PREPK
2546
ARRET
2551
SQPEL
2556
DYRNS
2561
YEIEY
2566
MEKIG
2571
SSLPQ
2576
DDDAP
2581
KKQAL
2586
YLMFD
2591
TSQES
2596
PVKSS
2601
PVRMS
2606
ESPTP
2611
CSGSS
2616
FEETE
2621
ALVNT
2626
AAKNQ
2631
HPVPR
2636
GLAPN
2641
QESHL
2646
QVPEK
2651
SSQKE
2656
LEAMG
2661
LGTPS
2666
EAIEI
2671
TAPEG
2676
SFASA
2681
DALLS
2686
RLAHP
2691
VSLCG
2696
ALDYL
2701
EPDLA
2706
EKNPP
2711
LFAQK
2716
LQEEL
2721
EFAIM
2726
RIEAL
2731
KLARQ
2736
IALAS
2741
RSHQD
2746
AKREA
2751
AHPTD
2756
VSISK
2761
TALYS
2766
RIGTA
2771
EVEKP
2776
AGLLF
2781
QQPDL
2786
DSALQ
2791
IARAE
2796
IITKE
2801
REVSE
2806
WKDKY
2811
EESRR
2816
EVMEM
2821
RKIVA
2826
EYEKT
2831
IAQMI
2836
EDEQR
2841
EKSVS
2846
HQTVQ
2851
QLVLE
2856
KEQAL
2861
ADLNS
2866
VEKSL
2871
ADLFR
2876
RYEKM
2881
KEVLE
2886
GFRKN
2891
EEVLK
2896
RCAQE
2901
YLSRV
2906
KKEEQ
2911
RYQAL
2916
KVHAE
2921
EKLDR
2926
ANAEI
2931
AQVRG
2936
KAQQE
2941
QAAHQ
2946
ASLRK
2951
EQLRV
2956
DALER
2961
TLEQK
2966
NKEIE
2971
ELTKI
2976
CDELI
2981
AKMGK
2986
S
2991
Mutation Information
DNA mutation:
c.A1673G
Peptide Range:
546 ~ 570
Mut AA position:
558 (13 in Wild Type peptide)
Alignment
Wild Type:
"PPGPTDGAKVHEDSTSPAVAKEGSR
||||||||||||.||||||||||||
Mutant:
PPGPTDGAKVHEGSTSPAVAKEGSR"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TACC2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
PPGPTDGAKVHEGSTSPAVAKEGSR
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT