Immunogenicity 1740
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
OTOP1
Transcript ID
ENST00000296358
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO
No TCR info found!
Full length protein sequence (612 aa)
MLEGL
1
GSPAS
6
PRAAA
11
SASVA
16
GSSGP
21
AACSP
26
PSSSA
31
PRSPE
36
SPAPR
41
RGGVR
46
ASVPQ
51
KLAEM
56
LSSQY
61
GLIVF
66
VAGLL
71
LLLAW
76
AVHAA
81
GVSKS
86
DLLCF
91
LTALM
96
LLQLL
101
WMLWY
106
VGRSS
111
AHRRL
116
FRLKD
121
THAGA
126
GWLRG
131
SITLF
136
AVITV
141
ILGCL
146
KIGYF
151
IGFSE
156
CLSAT
161
EGVFP
166
VTHSV
171
HTLLQ
176
VYFLW
181
GHAKD
186
IIQSF
191
KTLER
196
FGVIH
201
SVFTN
206
LLLWA
211
NGVLN
216
ESKHQ
221
LNEHK
226
ERLIT
231
LGFGN
236
ITTVL
241
DDHTP
246
QCNCT
251
PPTLC
256
TAISH
261
GIYYL
266
YPFNI
271
EYQIL
276
ASTML
281
YVLWK
286
NIGRK
291
VDSHQ
296
HQKMQ
301
FKSDG
306
VMVGA
311
VLGLT
316
VLAAT
321
IAVVV
326
VYLIH
331
IGRSK
336
TKSES
341
ALIMF
346
YLYAI
351
TLLML
356
MGAAG
361
LAGIR
366
IYRID
371
EKSLD
376
ESKNP
381
ARKLD
386
SDLLV
391
GTASG
396
SWLIS
401
WGSIL
406
AILCA
411
EGHPR
416
YTWYN
421
LPYSI
426
LAIVE
431
KYIQN
436
LFIFE
441
SIHRE
446
PEKLS
451
EDIQT
456
LRVVT
461
VCNGN
466
TMPLA
471
SSCPK
476
SGGVA
481
RDVAP
486
QGKDM
491
PPAAN
496
GNVCM
501
RESHD
506
KEEEK
511
QEESS
516
WGGSP
521
SPVRL
526
PRFLQ
531
GNAKR
536
KVLRN
541
IAAFL
546
FLCNI
551
SLWIP
556
PAFGC
561
RPEYD
566
NGLEE
571
IVFGF
576
EPWII
581
VVNLA
586
MPFSI
591
FYRMH
596
AAASL
601
FEVYC
606
KI
611
Mutation Information
DNA mutation:
None
Peptide Range:
94 ~ 118
Mut AA position:
106 (13 in Wild Type peptide)
Alignment
Wild Type:
"CFLTALMLLQLLWMLWYVGRSSAHR
||||||||||||.||||||||||||
Mutant:
CFLTALMLLQLLRMLWYVGRSSAHR"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) OTOP1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay