Immunogenicity 1750

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SORCS3
Transcript ID
ENST00000369701
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (1222 aa)
MEAAR
1
TERPA
6
GRPGA
11
PLVRT
16
GLLLL
21
STWVL
26
AGAEI
31
TWDAT
36
GGPGR
41
PAAPA
46
SRPPA
51
LSPLS
56
PRAVA
61
SQWPE
66
ELASA
71
RRAAV
76
LGRRA
81
GPELL
86
PQQGG
91
GRGGE
96
MQVEA
101
GGTSP
106
AGERR
111
GRGIP
116
APAKL
121
GGARR
126
SRRAQ
131
PPITQ
136
ERGDA
141
WATAP
146
ADGSR
151
GSRPL
156
AKGSR
161
EEVKA
166
PRAGG
171
SAAED
176
LRLPS
181
TSFAL
186
TGDSA
191
HNQAM
196
VHWSG
201
HNSSV
206
ILILT
211
KLYDF
216
NLGSV
221
TESSL
226
WRSTD
231
YGTTY
236
EKLND
241
KVGLK
246
TVLSY
251
LYVNP
256
TNKRK
261
IMLLS
266
DPEME
271
SSILI
276
SSDEG
281
ATYQK
286
YRLTF
291
YIQSL
296
LFHPK
301
QEDWV
306
LAYSL
311
DQKLY
316
SSMDF
321
GRRWQ
326
LMHER
331
ITPNR
336
FYWSV
341
AGLDK
346
EADLV
351
HMEVR
356
TTDGY
361
AHYLT
366
CRIQE
371
CAETT
376
RSGPF
381
ARSID
386
ISSLV
391
VQDEY
396
IFIQV
401
TTSGR
406
ASYYV
411
SYRRE
416
AFAQI
421
KLPKY
426
SLPKD
431
MHIIS
436
TDENQ
441
VFAAV
446
QEWNQ
451
NDTYN
456
LYISD
461
TRGIY
466
FTLAM
471
ENIKS
476
SRGLM
481
GNIII
486
ELYEV
491
AGIKG
496
IFLAN
501
KKVDD
506
QVKTY
511
ITYNK
516
GRDWR
521
LLQAP
526
DVDLR
531
GSPVH
536
CLLPF
541
CSLHL
546
HLQLS
551
ENPYS
556
SGRIS
561
SKETA
566
PGLVV
571
ATGNI
576
GPELS
581
YTDIG
586
VFISS
591
DGGNT
596
WRQIF
601
DEEYN
606
VWFLD
611
WGGAL
616
VAMKH
621
TPLPV
626
RHLWV
631
SFDEG
636
HSWDK
641
YGFTS
646
VPLFV
651
DGALV
656
EAGME
661
THIMT
666
VFGHF
671
SLRSE
676
WQLVK
681
VDYKS
686
IFSRH
691
CTKED
696
YQTWH
701
LLNQG
706
EPCVM
711
GERKI
716
FKKRK
721
PGAQC
726
ALGRD
731
HSGSV
736
VSEPC
741
VCANW
746
DFECD
751
YGYER
756
HGESQ
761
CVPAF
766
WYNPA
771
SPSKD
776
CSLGQ
781
SYLNS
786
TGYRR
791
IVSNN
796
CTDGL
801
REKYT
806
AKAQM
811
CPGKA
816
PRGLH
821
VVTTD
826
GRLVA
831
EQGHN
836
ATFII
841
LMEEG
846
DLQRT
851
NIQLD
856
FGDGI
861
AVSYA
866
NFSPI
871
EDGIK
876
HVYKS
881
AGIFQ
886
VTAYA
891
ENNLG
896
SDTAV
901
LFLHV
906
VCPVE
911
HVHLR
916
VPFVA
921
IRNKE
926
VNISA
931
VVWPS
936
QLGTL
941
TYFWW
946
FGNST
951
KPLIT
956
LDSSI
961
SFTFL
966
AEGTD
971
TITVQ
976
VAAGN
981
ALIQD
986
TKEIA
991
VHEYF
996
QSQLL
1001
SFSPN
1006
LDYHN
1011
PDIPE
1016
WRKDI
1021
GNVIK
1026
RALVK
1031
VTSVP
1036
EDQIL
1041
IAVFP
1046
GLPTS
1051
AELFI
1056
LPPKN
1061
LTERR
1066
KGNEG
1071
DLEQI
1076
VETLF
1081
NALNQ
1086
NLVQF
1091
ELKPG
1096
VQVIV
1101
YVTQL
1106
TLAPL
1111
VDSSA
1116
GHSSS
1121
AMLML
1126
LSVVF
1131
VGLAV
1136
FLIYK
1141
FKRKI
1146
PWINI
1151
YAQVQ
1156
HDKEQ
1161
EMIGS
1166
VSQSE
1171
NAPKI
1176
TLSDF
1181
TEPEE
1186
LLDKE
1191
LDTRV
1196
IGGIA
1201
TIANS
1206
ESTKE
1211
IPNCT
1216
SV
1221
Mutation Information
DNA mutation:
None
Peptide Range:
160 ~ 184
Mut AA position:
172 (13 in Wild Type peptide)
Alignment
Wild Type:
"LAKGSREEVKAPRAGGSAAEDLRLP
||||||||||||.||||||||||||
Mutant:
LAKGSREEVKAPWAGGSAAEDLRLP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SORCS3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay