Immunogenicity 1762

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TNXB
Transcript ID
ENST00000479795
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (842 aa)
MMPAQ
1
YALTS
6
SLVLL
11
VLLST
16
ARAGP
21
FSSRS
26
NVTLP
31
APRPP
36
PQPGG
41
HTVGA
46
GVGSP
51
SSQLY
56
EHTVE
61
GGEKQ
66
VVFTH
71
RINLP
76
PSTGC
81
GCPPG
86
TEPPV
91
LASEV
96
QALRV
101
RLEIL
106
EELVK
111
GLKEQ
116
CTGGC
121
CPASA
126
QAGTG
131
QTDVR
136
TLCSL
141
HGVFD
146
LSRCT
151
CSCEP
156
GWGGP
161
TCSDP
166
TDAEI
171
PPSSP
176
PSASG
181
SCPDD
186
CNDQG
191
RCVRG
196
RCVCF
201
PGYTG
206
PSCGW
211
PSCPG
216
DCQGR
221
GRCVQ
226
GVCVC
231
RAGFS
236
GPDCS
241
QRSCP
246
RGCSQ
251
RGRCE
256
GGRCV
261
CDPGY
266
TGDDC
271
GMRSC
276
PRGCS
281
QRGRC
286
ENGRC
291
VCNPG
296
YTGED
301
CGVRS
306
CPRGC
311
SQRGR
316
CKDGR
321
CVCDP
326
GYTGE
331
DCGTR
336
SCPWD
341
CGEGG
346
RCVDG
351
RCVCW
356
PGYTG
361
EDCST
366
RTCPR
371
DCRGR
376
GRCED
381
GECIC
386
DTGYS
391
GDDCG
396
VRSCP
401
GDCNQ
406
RGRCE
411
DGRCV
416
CWPGY
421
TGTDC
426
GSRAC
431
PRDCR
436
GRGRC
441
ENGVC
446
VCNAG
451
YSGED
456
CGVRS
461
CPGDC
466
RGRGR
471
CESGR
476
CMCWP
481
GYTGR
486
DCGTR
491
ACPGD
496
CRGRG
501
RCVDG
506
RCVCN
511
PGFTG
516
EDCGS
521
RRCPG
526
DCRGH
531
GLCED
536
GVCVC
541
DAGYS
546
GEDCS
551
TRSCP
556
GGCRG
561
RGQCL
566
DGRCV
571
CEDGY
576
SGEDC
581
GVRQC
586
PNDCS
591
QHGVC
596
QDGVC
601
ICWEG
606
YVSED
611
CSIRT
616
CPSNC
621
HGRGR
626
CEEGR
631
CLCDP
636
GYTGP
641
TCATR
646
MCPAD
651
CRGRG
656
RCVQG
661
VCLCH
666
VGYGG
671
EDCGQ
676
EEPPA
681
SACPG
686
GCGPR
691
ELCRA
696
GQCVC
701
VEGFR
706
GPDCA
711
IQTCP
716
GDCRG
721
RGECH
726
DGSCV
731
CKDGY
736
AGEDC
741
GEEVP
746
TIEGM
751
RMHLL
756
EETTV
761
RTEWT
766
PAPGP
771
VDAYE
776
IQFIP
781
TASPL
786
LCSAS
791
PHSPA
796
KAEAE
801
ISTSW
806
RNQDS
811
LNFFF
816
CLNIF
821
FCCCY
826
KNTLI
831
TRQEF
836
GN
841
Mutation Information
DNA mutation:
None
Peptide Range:
782 ~ 806
Mut AA position:
794 (13 in Wild Type peptide)
Alignment
Wild Type:
"QFIPTASPLLCSASPHSPAKAEAEI
||||||||||||.||||||||||||
Mutant:
QFIPTASPLLCSSSPHSPAKAEAEI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000168477

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay