Immunogenicity 1776
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
ADAMTS20
Transcript ID
ENST00000389420
HLA INFO
C*08:02
TCR INFO
No TCR info found!
Full length protein sequence (1910 aa)
MWVAK
1
WLTGL
6
LYHLS
11
LFITR
16
SWEVD
21
FHPRQ
26
EALVR
31
TLTSY
36
EVVIP
41
ERVNE
46
FGEVF
51
PQSHH
56
FSRQK
61
RSSEA
66
LEPMP
71
FRTHY
76
RFTAY
81
GQLFQ
86
LNLTA
91
DASFL
96
AAGYT
101
EVHLG
106
TPERG
111
AWESD
116
AGPSD
121
LRHCF
126
YRGQV
131
NSQED
136
YKAVV
141
SLCGG
146
LTGTF
151
KGQNG
156
EYFLE
161
PIMKA
166
DGNEY
171
EDGHN
176
KPHLI
181
YRQDL
186
NNSFL
191
QTLKY
196
CSVSE
201
SQIKE
206
TSLPF
211
HTYSN
216
MNEDL
221
NVMKE
226
RVLGH
231
TSKNV
236
PLKDE
241
RRHSR
246
KKRLI
251
SYPRY
256
IEIMV
261
TADAK
266
VVSAH
271
GSNLQ
276
NYILT
281
LMSIV
286
ATIYK
291
DPSIG
296
NLIHI
301
VVVKL
306
VMIHR
311
EEEGP
316
VINFD
321
GATTL
326
KNFCS
331
WQQTQ
336
NDLDD
341
VHPSH
346
HDTAV
351
LITRE
356
DICSS
361
KEKCN
366
MLGLS
371
YLGTI
376
CDPLQ
381
SCFIN
386
EEKGL
391
ISAFT
396
IAHEL
401
GHTLG
406
VQHDD
411
NPRCK
416
EMKVT
421
KYHVM
426
APALS
431
FHMSP
436
WSWSN
441
CSRKY
446
VTEFL
451
DTGYG
456
ECLLD
461
KPDEE
466
IYNLP
471
SELPG
476
SRYDG
481
NKQCE
486
LAFGP
491
GSQMC
496
PHINI
501
CMHLW
506
CTSTE
511
KLHKG
516
CFTQH
521
VPPAD
526
GTDCG
531
PGMHC
536
RHGLC
541
VNKET
546
ETRPV
551
NGEWG
556
PWEPY
561
SSCSR
566
TCGGG
571
IESAT
576
RRCNR
581
PEPRN
586
GGNYC
591
VGRRM
596
KFRSC
601
NTDSC
606
PKGTQ
611
DFREK
616
QCSDF
621
NGKHL
626
DISGI
631
PSNVR
636
WLPRY
641
SGIGT
646
KDRCK
651
LYCQV
656
AGTNY
661
FYLLK
666
DMVED
671
GTPCG
676
TETHD
681
ICVQG
686
QCMAA
691
GCDHV
696
LNSSA
701
KIDKC
706
GVCGG
711
DNSSC
716
KTITG
721
VFNSS
726
HYGYN
731
VVVKI
736
PAGAT
741
NVDIR
746
QYSYS
751
GQPDD
756
SYLAL
761
SDAEG
766
NFLFN
771
GNFLL
776
STSKK
781
EINVQ
786
GTRTV
791
IEYSG
796
SNNAV
801
ERINS
806
TNRQE
811
KELIL
816
QVLCV
821
GNLYN
826
PDVHY
831
SFNIP
836
LEERS
841
DMFTW
846
DPYGP
851
WEGCT
856
KMCQG
861
LQRRN
866
ITCIH
871
KSDHS
876
VVSDK
881
ECDHL
886
PLPSF
891
VTQSC
896
NTDCE
901
LRWHV
906
IGKSE
911
CSSQC
916
GQGYR
921
TLDIH
926
CMKYS
931
IHEGQ
936
TVQVD
941
DHYCG
946
DQLKP
951
PTQEL
956
CHGNC
961
VFTRW
966
HYSEW
971
SQCSR
976
SCGGG
981
ERSRE
986
SYCMN
991
NFGHR
996
LADNE
1001
CQELS
1006
RVTRE
1011
NCNEF
1016
SCPSW
1021
AASEW
1026
SECLV
1031
TCGKG
1036
TKQRQ
1041
VWCQL
1046
NVDHL
1051
SDGFC
1056
NSSTK
1061
PESLS
1066
PCELH
1071
TCASW
1076
QVGPW
1081
GPCTT
1086
TCGHG
1091
YQMRD
1096
VKCVN
1101
ELASA
1106
VLEDT
1111
ECHEA
1116
SRPSD
1121
RQSCV
1126
LTPCS
1131
FISKL
1136
ETALL
1141
PTVLI
1146
KKMAQ
1151
WRHGS
1156
WTPCS
1161
VSCGR
1166
GTQAR
1171
YVSCR
1176
DALDR
1181
IADES
1186
YCAHL
1191
PRPAE
1196
IWDCF
1201
TPCGE
1206
WQAGD
1211
WSPCS
1216
ASCGH
1221
GKTTR
1226
QVLCM
1231
NYHQP
1236
IDENY
1241
CDPEV
1246
RPLME
1251
QECSL
1256
AACPP
1261
AHSHF
1266
PSSPV
1271
QPSYY
1276
LSTNL
1281
PLTQK
1286
LEDNE
1291
NQVVH
1296
PSVRG
1301
NQWRT
1306
GPWGS
1311
CSSSC
1316
SGGLQ
1321
HRAVV
1326
CQDEN
1331
GQSAS
1336
YCDAA
1341
SKPPE
1346
LQQCG
1351
PGPCP
1356
QWNYG
1361
NWGEC
1366
SQTCG
1371
GGIKS
1376
RLVIC
1381
QFPNG
1386
QILED
1391
HNCEI
1396
VNKPP
1401
SVIQC
1406
HMHAC
1411
PADVS
1416
WHQEP
1421
WTSCS
1426
ASCGK
1431
GRKYR
1436
EVFCI
1441
DQFQR
1446
KLEDT
1451
NCSQV
1456
QKPPT
1461
HKACR
1466
SVRCP
1471
SWKAN
1476
SWNEC
1481
SVTCG
1486
SGVQQ
1491
RDVYC
1496
RLKGV
1501
GQVVE
1506
EMCDQ
1511
STRPC
1516
SQRRC
1521
WSQDC
1526
VQHKG
1531
MERGR
1536
LNCST
1541
SCERK
1546
DSHQR
1551
MECTD
1556
NQIRQ
1561
VNEIV
1566
YNSST
1571
ISLTS
1576
KNCRN
1581
PPCNY
1586
IVVTA
1591
DSSQC
1596
ANNCG
1601
FSYRQ
1606
RITYC
1611
TEIPS
1616
TKKHK
1621
LHRLR
1626
PIVYQ
1631
ECPVV
1636
PSSQV
1641
YQCIN
1646
SCLHL
1651
ATWKV
1656
GKWSK
1661
CSVTC
1666
GIGIM
1671
KRQVK
1676
CITKH
1681
GLSSD
1686
LCLNH
1691
LKPGA
1696
QKKCY
1701
ANDCK
1706
SFTTC
1711
KEIQV
1716
KNHIR
1721
KDGDY
1726
YLNIK
1731
GRIIK
1736
IYCAD
1741
MYLEN
1746
PKEYL
1751
TLVQG
1756
EENFS
1761
EVYGF
1766
RLKNP
1771
YQCPF
1776
NGSRR
1781
EDCEC
1786
DNGHL
1791
AAGYT
1796
VFSKI
1801
RIDLT
1806
SMQIK
1811
TTDLL
1816
FSKTI
1821
FGNAV
1826
PFATA
1831
GDCYS
1836
AFRCP
1841
QGQFS
1846
INLSG
1851
TGMKI
1856
SSTAK
1861
WLTQG
1866
SYTSV
1871
SIRRS
1876
EDGTR
1881
FFGKC
1886
GGYCG
1891
KCLPH
1896
MTTGL
1901
PIQVI
1906
Mutation Information
DNA mutation:
None
Peptide Range:
650 ~ 674
Mut AA position:
662 (13 in Wild Type peptide)
Alignment
Wild Type:
"TKDRCKLYCQVAGTNYFYLLKDMVE
||||||||||||.||||||||||||
Mutant:
TKDRCKLYCQVAATNYFYLLKDMVE"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) ADAMTS20
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay