Immunogenicity 178
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
TCF7L2
Transcript ID
uc021pyp.1
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (649 aa)
MPQLN
1
GGGGD
6
DLGAN
11
DELIS
16
FKDEG
21
EQEEK
26
SSENS
31
SAERD
36
LADVK
41
SSLVN
46
ESETN
51
QNSSS
56
DSEAE
61
RRPPP
66
RSESF
71
RDKSR
76
ESLEE
81
AAKRQ
86
DGGLF
91
KGPPY
96
PGYPF
101
IMIPD
106
LTSPY
111
LPNGS
116
LSPTA
121
RTYLQ
126
MKWPL
131
LDVQA
136
GSLQS
141
RQALK
146
DARSP
151
SPAHI
156
VQSPL
161
PCCTQ
166
GHDCQ
171
HFYPP
176
SDFTV
181
STQVF
186
RDMKR
191
SHSLQ
196
KVGEP
201
WCIES
206
NKVPV
211
VQHPH
216
HVHPL
221
TPLIT
226
YSNEH
231
FTPGN
236
PPPHL
241
PADVD
246
PKTGI
251
PRPPH
256
PPDIS
261
PYYPL
266
SPGTV
271
GQIPH
276
PLGWL
281
VPQQG
286
QPVYP
291
ITTGG
296
FRHPY
301
PTALT
306
VNASM
311
SSFLS
316
SRFPP
321
HMVPP
326
HHTLH
331
TTGIP
336
HPAIV
341
TPTVK
346
QESSQ
351
SDVGS
356
LHSSK
361
HQDSK
366
KEEEK
371
KKPHI
376
KKPLN
381
AFMLY
386
MKEMR
391
AKVVA
396
ECTLK
401
ESAAI
406
NQILG
411
RRWHA
416
LSREE
421
QAKYY
426
ELARK
431
ERQLH
436
MQLYP
441
GWSAR
446
DNYGK
451
KKKRK
456
RDKQP
461
GETNE
466
HSECF
471
LNPCL
476
SLPPI
481
TDANT
486
PKKCR
491
ALFGL
496
DRQTL
501
WCKPC
506
RRKKK
511
CVRYI
516
QGEGS
521
CLSPP
526
SSDGS
531
LLDSP
536
PPSPN
541
LLGSP
546
PRDAK
551
SQTEQ
556
TQPLS
561
LSLKP
566
DPLAH
571
LSMMP
576
PPPAL
581
LLAEA
586
THKAS
591
ALCPN
596
GALDL
601
PPAAL
606
QPAAP
611
SSSIA
616
QPSTS
621
SLHSH
626
SSLAG
631
TQPQP
636
LSLVT
641
KSLE
646
Mutation Information
DNA mutation:
c.C1246T
Peptide Range:
438 ~ 462
Mut AA position:
None (None in Wild Type peptide)
Alignment
Wild Type:
"QLHMQLYPGWSARDNYGKKKKRKRD
||||||||||||.||||||||||||
Mutant:
QLHMQLYPGWSAWDNYGKKKKRKRD"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TCF7L2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
QLHMQLYPGWSAWDNYGKKKKRKRD
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT