Immunogenicity 179
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
ITIH5
Transcript ID
uc021pmv.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (967 aa)
MLLLL
1
GLCLG
6
LSLCV
11
GSQEE
16
AQSWG
21
HSSEQ
26
DGLRV
31
PRQVR
36
LLQRL
41
KTKPL
46
MTEFS
51
VKSTI
56
ISRYA
61
FTTVS
66
CRMLN
71
RASED
76
QDIEF
81
QMQIP
86
AAAFI
91
TNFTM
96
LIGDK
101
VYQGE
106
ITERE
111
KKSGD
116
RVKEK
121
RNKTT
126
EENGE
131
KGTEI
136
FRASA
141
VIPSK
146
DKAAF
151
FLSYE
156
ELLQR
161
RLGKY
166
EHSIS
171
VRPQQ
176
LSGRL
181
SVDVN
186
ILESA
191
GIASL
196
EVLPL
201
HNSRQ
206
RGSGR
211
GEDDS
216
GPPPS
221
TVINQ
226
NETFA
231
NIIFK
236
PTVVQ
241
QARIA
246
QNGIL
251
GDFII
256
RYDVN
261
REQSI
266
GDIQV
271
LNGYF
276
VHYFA
281
PKDLP
286
PLPKN
291
VVFVL
296
DSSAS
301
MVGTK
306
LRQDI
311
GFSLA
316
VQNWV
321
PKGYL
326
DISCV
331
TLQTK
336
DALFT
341
ILHDL
346
RPQDR
351
FSIIG
356
FSNRI
361
KVWKD
366
HLISV
371
TPDSI
376
RDGKV
381
YIHHM
386
SPTGG
391
TDING
396
ALQRA
401
IRLLN
406
KYVAH
411
SGIGD
416
RSVSL
421
IVFLT
426
DGKPT
431
VGETH
436
TLKIL
441
NNTRE
446
AARGQ
451
VCIFT
456
IGIGN
461
DVDFR
466
LLEKL
471
SLENC
476
GLTRR
481
VHEEE
486
DAGSQ
491
LIGFY
496
DEIRT
501
PLLSD
506
IRIDY
511
PPSSV
516
VQATK
521
TLFPN
526
YFNGS
531
EIIIA
536
GKLVD
541
RKLDH
546
LHVEV
551
TASNS
556
KKFII
561
LKTDV
566
PVRPQ
571
KAGKD
576
VTGSP
581
RPGGD
586
GEGDT
591
NHIER
596
LWSYL
601
TTKEL
606
LSSWL
611
QSDDE
616
PEKER
621
LRQRA
626
QALAV
631
SYRFL
636
TPFTS
641
MKLRG
646
PVPRM
651
DGLEE
656
AHGMS
661
AAMGP
666
EPVVQ
671
SVRGA
676
GTQPG
681
PLLKK
686
PYQPR
691
IKISK
696
TSVDG
701
DPHFV
706
VDFPL
711
SRLTV
716
CFNID
721
GQPGD
726
ILRLV
731
SDHRD
736
SGVTV
741
NGELI
746
GAPAP
751
PNGHK
756
KQRTY
761
LRTIT
766
ILINK
771
PERSY
776
LEITP
781
SRVIL
786
DGGDR
791
LVLPC
796
NQSVV
801
VGSWG
806
LEVSV
811
SANAN
816
VTVTI
821
QGSIA
826
FVILI
831
HLYKK
836
PAPFQ
841
RHHLG
846
FYIAN
851
SEGLS
856
SNCHG
861
LLGQF
866
LNQDA
871
RLTED
876
PAGPS
881
QNLTH
886
PLLLQ
891
VGEGP
896
EAVLT
901
VKGHQ
906
VPVVW
911
KQRKI
916
YNGEE
921
QIDCW
926
FARNN
931
AAKLI
936
DGEYK
941
DYLAS
946
HPFDT
951
GMTLG
956
RGMSR
961
EL
966
Mutation Information
DNA mutation:
c.C83T
Peptide Range:
16 ~ 40
Mut AA position:
28 (13 in Wild Type peptide)
Alignment
Wild Type:
"GSQEEAQSWGHSSEQDGLRVPRQVR
||||||||||||.||||||||||||
Mutant:
GSQEEAQSWGHSLEQDGLRVPRQVR"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) ITIH5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
GSQEEAQSWGHSLEQDGLRVPRQVR
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT