Immunogenicity 1825

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
BEST2
Transcript ID
ENST00000042931
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (509 aa)
MTVTY
1
TARVA
6
NARFG
11
GFSQL
16
LLLWR
21
GSIYK
26
LLWRE
31
LLCFL
36
GFYMA
41
LSAAY
46
RFVLT
51
EGQKR
56
YFEKL
61
VIYCD
66
QYASL
71
IPVSF
76
VLGFY
81
VTLVV
86
NRWWS
91
QYLCM
96
PLPDA
101
LMCVV
106
AGTVH
111
GRDDR
116
GRLYR
121
RTLMR
126
YAGLS
131
AVLIL
136
RSVST
141
AVFKR
146
FPTID
151
HVVEA
156
GFMTR
161
EERKK
166
FENLN
171
SSYNK
176
YWVPC
181
VWFSN
186
LAAQA
191
RREGR
196
IRDNS
201
ALKLL
206
LEELN
211
VFRGK
216
CGMLF
221
HYDWI
226
SVPLV
231
YTQVV
236
TIALY
241
SYFLA
246
CLIGR
251
QFLDP
256
AQGYK
261
DHDLD
266
LCVPI
271
FTLLQ
276
FFFYA
281
GWLKV
286
AEQLI
291
NPFGE
296
DDDDF
301
ETNFL
306
IDRNF
311
QVSML
316
AVDEM
321
YDDLA
326
VLEKD
331
LYWDA
336
AEARA
341
PYTAA
346
TVFQL
351
RQPSF
356
QGSTF
361
DITLA
366
KEDMQ
371
FQRLD
376
GLDGP
381
MGEAP
386
GDFLQ
391
RLLPA
396
GAGMV
401
AGGPL
406
GRRLS
411
FLLRK
416
NSCVS
421
EASTG
426
ASCSC
431
AVVPE
436
GAAPE
441
CSCGD
446
PLLDP
451
GLPEP
456
EAPPP
461
AGPEP
466
LTLIP
471
GPVEP
476
FSIVT
481
MPGPR
486
GPAPP
491
WLPSP
496
IGEEE
501
ENLA
506
Mutation Information
DNA mutation:
None
Peptide Range:
54 ~ 78
Mut AA position:
66 (13 in Wild Type peptide)
Alignment
Wild Type:
"LTEGQKRYFEKLVIYCDQYASLIPV
||||||||||||.||||||||||||
Mutant:
LTEGQKRYFEKLLIYCDQYASLIPV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) BEST2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay