Immunogenicity 1842

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
UCP2
Transcript ID
ENST00000544615
HLA INFO
DRB*04:03
TCR INFO

No TCR info found!

T cell Tumor cell DRB*04:03
sequence
Full length protein sequence (282 aa)
GQHAY
1
PCSYP
6
VLALQ
11
IQGES
16
QGPVR
21
ATASA
26
QYRGV
31
MGTIL
36
TMVRT
41
EGPRS
46
LYNGL
51
VAGLQ
56
RQMSF
61
ASVRI
66
GLYDS
71
VKQFY
76
TKGSE
81
HASIG
86
SRLLA
91
GSTTG
96
ALAVA
101
VAQPT
106
DVVKV
111
RFQAQ
116
ARAGG
121
GRRYQ
126
STVNA
131
YKTIA
136
REEGF
141
RGLWK
146
GTSPN
151
VARNA
156
IVNCA
161
ELVTY
166
DLIKD
171
ALLKA
176
NLMTD
181
DLPCH
186
FTSAF
191
GAGFC
196
TTVIA
201
SPVDV
206
VKTRY
211
MNSAL
216
GQYSS
221
AGHCA
226
LTMLQ
231
KEGPR
236
AFYKG
241
FMPSF
246
LRLGS
251
WNVVM
256
FVTYE
261
QLKRA
266
LMAAC
271
TSREA
276
PF
281
Mutation Information
DNA mutation:
None
Peptide Range:
49 ~ 73
Mut AA position:
61 (13 in Wild Type peptide)
Alignment
Wild Type:
"RSLYNGLVAGLQRQMSFASVRIGLY
||||||||||||.||||||||||||
Mutant:
RSLYNGLVAGLQHQMSFASVRIGLY"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) UCP2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay