Immunogenicity 185

summary
Sample ID
4196
Response
Positive
Tumor Type
Colorectal cancer
Gene Symbol
TP53
Transcript ID
None
HLA INFO
A*02:01
TCR INFO

TRAJAV6

TRBVCALDIYPHDMRF

TRBDBV11

TRAVCASSEGLWQVGDEQYF

T cell Tumor cell A*02:01
sequence
Full length protein sequence (346 aa)
MEEPQ
1
SDPSV
6
EPPLS
11
QETFS
16
DLWKL
21
LPENN
26
VLSPL
31
PSQAM
36
DDLML
41
SPDDI
46
EQWFT
51
EDPGP
56
DEAPR
61
MPEAA
66
PPVAP
71
APAAP
76
TPAAP
81
APAPS
86
WPLSS
91
SVPSQ
96
KTYQG
101
SYGFR
106
LGFLH
111
SGTAK
116
SVTCT
121
YSPAL
126
NKMFC
131
QLAKT
136
CPVQL
141
WVDST
146
PPPGT
151
RVRAM
156
AIYKQ
161
SQHMT
166
EVVRR
171
CPHHE
176
RCSDS
181
DGLAP
186
PQHLI
191
RVEGN
196
LRVEY
201
LDDRN
206
TFRHS
211
VVVPY
216
EPPEV
221
GSDCT
226
TIHYN
231
YMCNS
236
SCMGG
241
MNRRP
246
ILTII
251
TLEDS
256
SGNLL
261
GRNSF
266
EVRVC
271
ACPGR
276
DRRTE
281
EENLR
286
KKGEP
291
HHELP
296
PGSTK
301
RALPN
306
NTSSS
311
PQPKK
316
KPLDG
321
EYFTL
326
QMLLD
331
LRWCY
336
FLINS
341
S
346
Mutation Information
DNA mutation:
None
Peptide Range:
168 ~ 176
Mut AA position:
175 (8 in Wild Type peptide)
Alignment
Wild Type:
"HMTEVVRRC
|||||||.|
Mutant:
HMTEVVRHC"
reference
clinic trial
Checkpoint Blockade

Pembrolizumab

ACT

Y

Vaccination

N

Curative Effect

N

experiment
minimal_peptide

HMTEVVRHC

Antigen Type

peptide

T-cell Source

TILs

APC Type

T2 cells

Assay

ELISPOT