Immunogenicity 1887
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCSK4
Transcript ID
ENST00000588195
HLA INFO
C*07:01
TCR INFO
No TCR info found!
Full length protein sequence (525 aa)
MRPAP
1
IALWL
6
RLVLA
11
LALVR
16
PRAVG
21
WAPVR
26
APIYV
31
SSWAV
36
QVSQG
41
NREVE
46
RLARK
51
FGFVN
56
LGPIF
61
PDGQY
66
FHLRH
71
RGVVQ
76
QSLTP
81
HWGHR
86
LHLKK
91
NPKVQ
96
WFQQQ
101
TLQRR
106
VKRSV
111
VVPTD
116
PWFSK
121
QWYMN
126
SEAQP
131
DLSIL
136
QAWSQ
141
GLSGQ
146
GIVVS
151
VLDDG
156
IEKDH
161
PDLWA
166
NYDPL
171
ASYDF
176
NDYDP
181
DPQPR
186
YTPSK
191
ENRRT
196
DAGRY
201
HHRCH
206
RGPVA
211
EPAAA
216
AHPHL
221
QRQLG
226
SRGRR
231
PHGGR
236
PRHPH
241
PRGLP
246
AWCDQ
251
GEWQP
256
EEGRG
261
GRPGR
266
RPLPA
271
PPGFP
276
GPRRA
281
GHALH
286
LGLGQ
291
RRPAL
296
RQLQL
301
RRLHQ
306
QHPHA
311
FRGQH
316
HPAGP
321
RALVQ
326
RSLRL
331
HPHHH
336
LQQRR
341
GHRPP
346
DRHHG
351
PASRV
356
HRPAH
361
GHLGL
366
SPTGG
371
RHDRP
376
SAGGQ
381
PVPDV
386
ERHAA
391
PGGPR
396
VQAGA
401
PAGRG
406
LEDQR
411
RGAPS
416
EPSLR
421
IRAAG
426
RRAAG
431
GHRPH
436
LAAHP
441
AAEEV
446
RRPGP
451
EPPHP
456
HPAAD
461
LHQGK
466
RIGLR
471
RPPQL
476
HPLAG
481
ARAGA
486
ADAVL
491
QPARR
496
PGDLA
501
HQPHG
506
HALHT
511
RGHTT
516
LGRQH
521
Mutation Information
DNA mutation:
None
Peptide Range:
402 ~ 426
Mut AA position:
414 (13 in Wild Type peptide)
Alignment
Wild Type:
"QAGAPAGRGLEDQRRGAPSEPSLRI
||||||||||||.||||||||||||
Mutant:
QAGAPAGRGLEDRRRGAPSEPSLRI"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) PCSK4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay