Immunogenicity 1912

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
GDF5OS
Transcript ID
ENST00000374375
HLA INFO
C*16:01
TCR INFO

No TCR info found!

T cell Tumor cell C*16:01
sequence
Full length protein sequence (250 aa)
MIQSS
1
QPMSL
6
KLTCS
11
AFRLQ
16
RALRF
21
LLGRL
26
PWRVA
31
SGARR
36
FRRWL
41
NRYSY
46
TVLSS
51
WPERA
56
LISLK
61
NRSRF
66
LVRPN
71
TRNRA
76
FSWTC
81
RAARS
86
KPRPR
91
RSTAL
96
PRSQA
101
SSSRH
106
SWAEF
111
LKFRK
116
SFQMS
121
NTSQP
126
DPSRP
131
GTERT
136
SSKEA
141
GCRPL
146
GQLDS
151
FSWAA
156
RPPPG
161
AAGLA
166
VSEGF
171
FRKIR
176
SSAPS
181
SPSFS
186
RALMS
191
NTYLC
196
FLTTG
201
PRSSR
206
ENTQK
211
SFPAT
216
SPREP
221
VTSRL
226
RGKAP
231
ALSPS
236
RELSF
241
TSAPF
246
Mutation Information
DNA mutation:
None
Peptide Range:
146 ~ 170
Mut AA position:
158 (13 in Wild Type peptide)
Alignment
Wild Type:
"GCRPLGQLDSFSWAARPPPGAAGLA
||||||||||||.||||||||||||
Mutant:
GCRPLGQLDSFSLAARPPPGAAGLA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000204183

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay