Immunogenicity 1913
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
KCNQ5
Transcript ID
ENST00000402622
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (942 aa)
MPRHH
1
AGGEE
6
GGAAG
11
LWVKS
16
GAAAA
21
AAGGG
26
RLGSG
31
MKDVE
36
SGRGR
41
VLLNS
46
AAARG
51
DGLLL
56
LGTRA
61
ATLGG
66
GGGGL
71
RESRR
76
GKQGA
81
RMSLL
86
GKPLS
91
YTSSQ
96
SCRRN
101
VKYRR
106
VQNYL
111
YNVLE
116
RPRGW
121
AFIYH
126
AFVFL
131
LVFGC
136
LILSV
141
FSTIP
146
EHTKL
151
ASSCL
156
LILEF
161
VMIVV
166
FGLEF
171
IIRIW
176
SAGCC
181
CRYRG
186
WQGRL
191
RFARK
196
PFCVI
201
DTIVL
206
IASIA
211
VVSAK
216
TQGNI
221
FATSA
226
LRSLR
231
FLQIL
236
RMVRM
241
DRRGG
246
TWKLL
251
GSVVY
256
AHSKE
261
LITAW
266
YIGFL
271
VLIFS
276
SFLVY
281
LVEKD
286
ANKEF
291
STYAD
296
ALWWG
301
TITLT
306
TIGYG
311
DKTPL
316
TWLGR
321
LLSAG
326
FALLG
331
ISFFA
336
LPAGI
341
LGSGF
346
ALKVQ
351
EQHRQ
356
KHFEK
361
RRNPA
366
ANLIQ
371
CVWRS
376
YAADE
381
KSVSI
386
ATWKP
391
HLKAL
396
HTCSP
401
TNKFC
406
SNKQK
411
LFRMY
416
TSRKQ
421
SQKLS
426
FKERV
431
RMASP
436
RGQSI
441
KSRQA
446
SVGDR
451
RSPST
456
DITAE
461
GSPTK
466
VQKSW
471
SFNDR
476
TRFRP
481
SLRLK
486
SSQPK
491
PVIDA
496
DTALG
501
TDDVY
506
DEKGC
511
QCDVS
516
VEDLT
521
PPLKT
526
VIRAI
531
RIMKF
536
HVAKR
541
KFKET
546
LRPYD
551
VKDVI
556
EQYSA
561
GHLDM
566
LCRIK
571
SLQTR
576
VDQIL
581
GKGQI
586
TSDKK
591
SREKI
596
TAEHE
601
TTDDL
606
SMLGR
611
VVKVE
616
KQVQS
621
IESKL
626
DCLLD
631
IYQQV
636
LRKGS
641
ASALA
646
LASFQ
651
IPPFE
656
CEQTS
661
DYQSP
666
VDSKD
671
LSGSA
676
QNSGC
681
LSRST
686
SANIS
691
RGLQF
696
ILTPN
701
EFSAQ
706
TFYAL
711
SPTMH
716
SQATQ
721
VPISQ
726
SDGSA
731
VAATN
736
TIANQ
741
INTAP
746
KPAAP
751
TTLQI
756
PPPLP
761
AIKHL
766
PRPET
771
LHPNP
776
AGLQE
781
SISDV
786
TTCLV
791
ASKEN
796
VQVAQ
801
SNLTK
806
DRSMR
811
KSFDM
816
GGETL
821
LSVCP
826
MVPKD
831
LGKSL
836
SVQNL
841
IRSTE
846
ELNIQ
851
LSGSE
856
SSGSR
861
GSQDF
866
YPKWR
871
ESKLF
876
ITDEE
881
VGPEE
886
TETDT
891
FDAAP
896
QPARE
901
AAFAS
906
DSLRT
911
GRSRS
916
SQSIC
921
KAGES
926
TDALS
931
LPHVK
936
LK
941
Mutation Information
DNA mutation:
None
Peptide Range:
158 ~ 182
Mut AA position:
170 (13 in Wild Type peptide)
Alignment
Wild Type:
"SCLLILEFVMIVVFGLEFIIRIWSA
||||||||||||.||||||||||||
Mutant:
SCLLILEFVMIVIFGLEFIIRIWSA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) KCNQ5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay