Immunogenicity 1931

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
LARP1
Transcript ID
ENST00000523163
HLA INFO
C*06:02
TCR INFO

No TCR info found!

T cell Tumor cell C*06:02
sequence
Full length protein sequence (281 aa)
DESGE
1
EKNGD
6
EDCQR
11
GGQKK
16
KGNKH
21
KWVPL
26
QIDMK
31
PEVPR
36
EKLAS
41
RPTRP
46
PEPRH
51
IPANR
56
GEIKA
61
HFDYQ
66
FGYRK
71
FDGVE
76
GPRTP
81
KYMNN
86
ITYYF
91
DNVSS
96
TELYS
101
VDQEL
106
LKDYI
111
KRQIE
116
YYFSV
121
DNLER
126
DFFLR
131
RKMDA
136
DGFLP
141
ITLIA
146
SFHRV
151
QALTT
156
DISLI
161
FAALK
166
DSKVV
171
EIVDE
176
KVRRR
181
EEPEK
186
WPLPP
191
IVDYS
196
QTDFS
201
QLLNC
206
PEFVP
211
RQHYQ
216
KETES
221
APGSP
226
RAVTP
231
VPTKT
236
EEVSN
241
LKTLP
246
KGLSA
251
SLPDL
256
DSENW
261
IEVKK
266
RPRPS
271
PARPK
276
K
281
Mutation Information
DNA mutation:
None
Peptide Range:
43 ~ 67
Mut AA position:
55 (13 in Wild Type peptide)
Alignment
Wild Type:
"LASRPTRPPEPRHIPANRGEIKAHF
||||||||||||.||||||||||||
Mutant:
LASRPTRPPEPRPIPANRGEIKAHF"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000155506

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay