Immunogenicity 195
Sample ID
KLE
Response
Positive
Tumor Type
Uterine carcinoma
Gene Symbol
TP53
Transcript ID
None
HLA INFO
A*02:01
TCR INFO
TRAJAV6
TRBVCALDIYPHDMRF
TRBDBV11
TRAVCASSEGLWQVGDEQYF
Full length protein sequence (346 aa)
MEEPQ
1
SDPSV
6
EPPLS
11
QETFS
16
DLWKL
21
LPENN
26
VLSPL
31
PSQAM
36
DDLML
41
SPDDI
46
EQWFT
51
EDPGP
56
DEAPR
61
MPEAA
66
PPVAP
71
APAAP
76
TPAAP
81
APAPS
86
WPLSS
91
SVPSQ
96
KTYQG
101
SYGFR
106
LGFLH
111
SGTAK
116
SVTCT
121
YSPAL
126
NKMFC
131
QLAKT
136
CPVQL
141
WVDST
146
PPPGT
151
RVRAM
156
AIYKQ
161
SQHMT
166
EVVRR
171
CPHHE
176
RCSDS
181
DGLAP
186
PQHLI
191
RVEGN
196
LRVEY
201
LDDRN
206
TFRHS
211
VVVPY
216
EPPEV
221
GSDCT
226
TIHYN
231
YMCNS
236
SCMGG
241
MNRRP
246
ILTII
251
TLEDS
256
SGNLL
261
GRNSF
266
EVRVC
271
ACPGR
276
DRRTE
281
EENLR
286
KKGEP
291
HHELP
296
PGSTK
301
RALPN
306
NTSSS
311
PQPKK
316
KPLDG
321
EYFTL
326
QMLLD
331
LRWCY
336
FLINS
341
S
346
Mutation Information
DNA mutation:
None
Peptide Range:
168 ~ 176
Mut AA position:
175 (8 in Wild Type peptide)
Alignment
Wild Type:
"HMTEVVRRC
|||||||.|
Mutant:
HMTEVVRHC"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) TP53
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
HMTEVVRHC
Antigen
Type
peptide
T-cell
Source
TILs
APC
Type
DCs
Assay
FACS