Immunogenicity 1952

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SLC8A1
Transcript ID
ENST00000402441
HLA INFO
B*14:02
TCR INFO

No TCR info found!

T cell Tumor cell B*14:02
sequence
Full length protein sequence (937 aa)
MYNMR
1
RLSLS
6
PTFSM
11
GFHLL
16
VTVSL
21
LFSHV
26
DHVIA
31
ETEME
36
GEGNE
41
TGECT
46
GSYYC
51
KKGVI
56
LPIWE
61
PQDPS
66
FGDKI
71
ARATV
76
YFVAM
81
VYMFL
86
GVSII
91
ADRFM
96
SSIEV
101
ITSQE
106
KEITI
111
KKPNG
116
ETTKT
121
TVRIW
126
NETVS
131
NLTLM
136
ALGSS
141
APEIL
146
LSVIE
151
VCGHN
156
FTAGD
161
LGPST
166
IVGSA
171
AFNMF
176
IIIAL
181
CVYVV
186
PDGET
191
RKIKH
196
LRVFF
201
VTAAW
206
SIFAY
211
TWLYI
216
ILSVI
221
SPGVV
226
EVWEG
231
LLTFF
236
FFPIC
241
VVFAW
246
VADRR
251
LLFYK
256
YVYKR
261
YRAGK
266
QRGMI
271
IEHEG
276
DRPSS
281
KTEIE
286
MDGKV
291
VNSHV
296
ENFLD
301
GALVL
306
EVDER
311
DQDDE
316
EARRE
321
MARIL
326
KELKQ
331
KHPDK
336
EIEQL
341
IELAN
346
YQVLS
351
QQQKS
356
RAFYR
361
IQATR
366
LMTGA
371
GNILK
376
RHAAD
381
QARKA
386
VSMHE
391
VNTEV
396
TENDP
401
VSKIF
406
FEQGT
411
YQCLE
416
NCGTV
421
ALTII
426
RRGGD
431
LTNTV
436
FVDFR
441
TEDGT
446
ANAGS
451
DYEFT
456
EGTVV
461
FKPGD
466
TQKEI
471
RVGII
476
DDDIF
481
EEDEN
486
FLVHL
491
SNVKV
496
SSEAS
501
EDGIL
506
EANHV
511
STLAC
516
LGSPS
521
TATVT
526
IFDDD
531
HAGIF
536
TFEEP
541
VTHVS
546
ESIGI
551
MEVKV
556
LRTSG
561
ARGNV
566
IVPYK
571
TIEGT
576
ARGGG
581
EDFED
586
TCGEL
591
EFQND
596
EIVKI
601
ITIRI
606
FDREE
611
YEKEC
616
SFSLV
621
LEEPK
626
WIRRG
631
MKGGF
636
TITDE
641
YDDKQ
646
PLTSK
651
EEEER
656
RIAEM
661
GRPIL
666
GEHTK
671
LEVII
676
EESYE
681
FKSTV
686
DKLIK
691
KTNLA
696
LVVGT
701
NSWRE
706
QFIEA
711
ITVSA
716
GEDDD
721
DDECG
726
EEKLP
731
SCFDY
736
VMHFL
741
TVFWK
746
VLFAF
751
VPPTE
756
YWNGW
761
ACFIV
766
SILMI
771
GLLTA
776
FIGDL
781
ASHFG
786
CTIGL
791
KDSVT
796
AVVFV
801
ALGTS
806
VPDTF
811
ASKVA
816
ATQDQ
821
YADAS
826
IGNVT
831
GSNAV
836
NVFLG
841
IGVAW
846
SIAAI
851
YHAAN
856
GEQFK
861
VSPGT
866
LAFSV
871
TLFTI
876
FAFIN
881
VGVLL
886
YRRRP
891
EIGGE
896
LGGPR
901
TAKLL
906
TSCLF
911
VLLWL
916
LYIFF
921
SSLEA
926
YCHIK
931
GF
936
Mutation Information
DNA mutation:
None
Peptide Range:
313 ~ 337
Mut AA position:
325 (13 in Wild Type peptide)
Alignment
Wild Type:
"DERDQDDEEARREMARILKELKQKH
||||||||||||.||||||||||||
Mutant:
DERDQDDEEARRQMARILKELKQKH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SLC8A1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay