Immunogenicity 1975

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
GNAO1
Transcript ID
ENST00000374943
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*06:03
sequence
Full length protein sequence (269 aa)
MSWKK
1
ALRIP
6
GDLRV
11
ATVTL
16
MLAML
21
SSLLA
26
EGRDS
31
PEDFV
36
FQFKG
41
MCYFT
46
NGTER
51
VRLVT
56
RYIYN
61
REEYA
66
RFDSD
71
VGVYR
76
AVTPQ
81
GRPDA
86
EYWNS
91
QKEVL
96
EGTRA
101
ELDTV
106
CRHNY
111
EVAFR
116
GILQR
121
RVEPT
126
VTISP
131
SRTEA
136
LNHHN
141
LLVCS
146
VTDFY
151
PGQIK
156
VRWFR
161
NDQEE
166
TAGVV
171
STPLI
176
RNGDW
181
TFQIL
186
VMLEM
191
TPQRG
196
DVYTC
201
HVEHP
206
SLQSP
211
ITVEW
216
RAQSE
221
SAQSK
226
MLSGV
231
GGFVL
236
GLIFL
241
GLGLI
246
IRQRS
251
QKGPQ
256
GPPPA
261
GLLH
266
Mutation Information
DNA mutation:
None
Peptide Range:
58 ~ 82
Mut AA position:
70 (13 in Wild Type peptide)
Alignment
Wild Type:
"LVTRYIYNREEYARFDSDVGVYRAV
||||||||||||.||||||||||||
Mutant:
LVTRYIYNREEYVRFDSDVGVYRAV"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HLA-DQB1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay