Immunogenicity 1983

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
DLGAP3
Transcript ID
ENST00000235180
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (979 aa)
MRGYH
1
GDRGS
6
HPRPA
11
RFADQ
16
QHMDV
21
GPAAR
26
APYLL
31
GSREA
36
FSTEP
41
RFCAP
46
RAGLG
51
HISPE
56
GPLSL
61
SEGPS
66
VGPEG
71
GPAGA
76
GVGGG
81
SSTFP
86
RMYPG
91
QGPFD
96
TCEDC
101
VGHPQ
106
GKGAP
111
RLPPT
116
LLDQF
121
EKQLP
126
VQQDG
131
FHTLP
136
YQRGP
141
AGAGP
146
GPAPG
151
TGTAP
156
EPRSE
161
SPSRI
166
RHLVH
171
SVQKL
176
FAKSH
181
SLEAP
186
GKRDY
191
NGPKA
196
EGRGG
201
SGGDS
206
YPGPG
211
SGGPH
216
TSHHH
221
HHHHH
226
HHHHQ
231
SRHGK
236
RSKSK
241
DRKGD
246
GRHQA
251
KSTGW
256
WSSDD
261
NLDSD
266
SGFLA
271
GGRPP
276
GEPGG
281
PFCLE
286
GPDGS
291
YRDLS
296
FKGRS
301
GGSEG
306
RCLAC
311
TGMSM
316
SLDGQ
321
SVKRS
326
AWHTM
331
MVSQG
336
RDGYP
341
GAGPG
346
KGLLG
351
PETKA
356
KARTY
361
HYLQV
366
PQDDW
371
GGYPT
376
GGKDG
381
EIPCR
386
RMRSG
391
SYIKA
396
MGDEE
401
SGDSD
406
GSPKT
411
SPKAV
416
ARRFT
421
TRRSS
426
SVDQA
431
RINCC
436
VPPRI
441
HPRSS
446
IPGYS
451
RSLTT
456
GQLSD
461
ELNQQ
466
LEAVC
471
GSVFG
476
ELESQ
481
AVDAL
486
DLPGC
491
FRMRS
496
HSYLR
501
AIQAG
506
CSQDD
511
DCLPL
516
LATPA
521
AVSGR
526
PGSSF
531
NFRKA
536
PPPIP
541
PGSQA
546
PPRIS
551
ITAQS
556
STDSA
561
HESFT
566
AAEGP
571
ARRCS
576
SADGL
581
DGPAM
586
GARTL
591
ELAPV
596
PPRAS
601
PKPPT
606
LIIKT
611
IPGRE
616
ELRSL
621
ARQRK
626
WRPSI
631
GVQVE
636
TISDS
641
DTENR
646
SRREF
651
HSIGV
656
QVEED
661
KRRAR
666
FKRSN
671
SVTAG
676
VQADL
681
ELEGL
686
AGLAT
691
VATED
696
KALQF
701
GRSFQ
706
RHASE
711
PQPGP
716
RAPTY
721
SVFRT
726
VHTQG
731
QWAYR
736
EGYPL
741
PYEPP
746
ATDGS
751
PGPAP
756
APTPG
761
PGAGR
766
RDSWI
771
ERGSR
776
SLPDS
781
GRASP
786
CPRDG
791
EWFIK
796
MLRAE
801
VEKLE
806
HWCQQ
811
MEREA
816
EDYEL
821
PEEIL
826
EKIRS
831
AVGST
836
QLLLS
841
QKVQQ
846
FFRLC
851
QQSMD
856
PTAFP
861
VPTFQ
866
DLAGF
871
WDLLQ
876
LSIED
881
VTLKF
886
LELQQ
891
LKANS
896
WKLLE
901
PKEEK
906
KVPPP
911
IPKKP
916
LRGRG
921
VPVKE
926
RSLDS
931
VDRQR
936
QEARK
941
RLLAA
946
KRAAS
951
FRHSS
956
ATESA
961
DSIEI
966
YIPEA
971
QTRL
976
Mutation Information
DNA mutation:
None
Peptide Range:
506 ~ 530
Mut AA position:
518 (13 in Wild Type peptide)
Alignment
Wild Type:
"AIQAGCSQDDDCLPLLATPAAVSGR
||||||||||||.||||||||||||
Mutant:
AIQAGCSQDDDCQPLLATPAAVSGR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) DLGAP3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay