Immunogenicity 1999
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
RASGRP4
Transcript ID
ENST00000426920
HLA INFO
DRB*08:01
TCR INFO
No TCR info found!
Full length protein sequence (484 aa)
MNRKD
1
SKRKS
6
HQECT
11
GKIGG
16
RGRPR
21
QVRRH
26
KTCPS
31
PREIS
36
KVMAS
41
MNLGL
46
LSEGG
51
CSEDE
56
LLEKC
61
IQSFD
66
SAGSL
71
CHEDH
76
MLNMV
81
LAMHS
86
WVLPS
91
ADLAA
96
RLLTS
101
YQKAT
106
GDTQE
111
LRRLQ
116
ICHLV
121
RYWLM
126
RHPEV
131
MHQDP
136
QLEEV
141
IGRFW
146
ATVAR
151
EGNSA
156
QRRLG
161
DSSDL
166
LSPGG
171
PGPPL
176
PMSSP
181
GLGKK
186
RKVSL
191
LFDHL
196
ETGEL
201
AQHLT
206
YLEFR
211
SFQAI
216
TLSLD
221
LFYTE
226
DEIYE
231
LSYAR
236
EPRCP
241
KSLPP
246
SPFNA
251
PLVVE
256
WAPGV
261
TPKPD
266
RVTLG
271
RHVEQ
276
LVESV
281
FKNYD
286
PEGRG
291
TISQE
296
DFERL
301
SGNFP
306
FACHG
311
LHPPP
316
RQGRG
321
SFSRE
326
ELTGY
331
LLRAS
336
AICSK
341
LGLAF
346
LHTFH
351
EVTFR
356
KPTFC
361
DSCSG
366
FLWGV
371
TKQGY
376
RCREC
381
GLCCH
386
KHCRD
391
QVKVE
396
CKKRP
401
GAKGD
406
AGPPG
411
APVPS
416
TPAPH
421
ASCGS
426
EENHS
431
YTLSL
436
EPETG
441
CQLRH
446
AWTQT
451
ESPHP
456
SWETD
461
TVPCP
466
VMDPP
471
STASS
476
KLDS
481
Mutation Information
DNA mutation:
None
Peptide Range:
212 ~ 236
Mut AA position:
224 (13 in Wild Type peptide)
Alignment
Wild Type:
"LEFRSFQAITLSLDLFYTEDEIYEL
||||||||||||.||||||||||||
Mutant:
LEFRSFQAITLSMDLFYTEDEIYEL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) RASGRP4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay