Immunogenicity 2014

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TGFBR1
Transcript ID
ENST00000374990
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (426 aa)
MEAAV
1
AAPRP
6
RLLLL
11
VLAAA
16
AAAAA
21
ALLPG
26
ATALQ
31
CFCHL
36
CTKDN
41
FTCVT
46
DGLCF
51
VSVTE
56
TTDKV
61
IHNSM
66
CIAEI
71
DLIPR
76
DRPFV
81
CAPSS
86
KTGSV
91
TTTYC
96
CNQDH
101
CNKIE
106
LPTTG
111
LPLLV
116
QRTIA
121
RTIVL
126
QESIG
131
KGRFG
136
EVWRG
141
KWRGE
146
EVAVK
151
IFSSR
156
EERSW
161
FREAE
166
IYQTV
171
MLRHE
176
NILGF
181
IAADN
186
KDNGT
191
WTQLW
196
LVSDY
201
HEHGS
206
LFDYL
211
NRYTV
216
TVEGM
221
IKLAL
226
STASG
231
LAHLH
236
MEIVG
241
TQGKP
246
AIAHR
251
DLKSK
256
NILVK
261
KNGTC
266
CIADL
271
GLAVR
276
HDSAT
281
DTIDI
286
APNHR
291
VGTKR
296
YMAPE
301
VLDDS
306
INMKH
311
FESFK
316
RADIY
321
AMGLV
326
FWEIA
331
RRCSI
336
GGIHE
341
DYQLP
346
YYDLV
351
PSDPS
356
VEEMR
361
KVVCE
366
QKLRP
371
NIPNR
376
WQSCE
381
ALRVM
386
AKIMR
391
ECWYA
396
NGAAR
401
LTALR
406
IKKTL
411
SQLSQ
416
QEGIK
421
M
426
Mutation Information
DNA mutation:
None
Peptide Range:
143 ~ 167
Mut AA position:
155 (13 in Wild Type peptide)
Alignment
Wild Type:
"WRGKWRGEEVAVKIFSSREERSWFR
||||||||||||.||||||||||||
Mutant:
WRGKWRGEEVAVNIFSSREERSWFR"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) TGFBR1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay