Immunogenicity 2025

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
XYLT1
Transcript ID
ENST00000261381
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*06:03
sequence
Full length protein sequence (959 aa)
MVAAP
1
CARRL
6
ARRSH
11
SALLA
16
ALTVL
21
LLQTL
26
VVWNF
31
SSLDS
36
GAGER
41
RGGAA
46
VGGGE
51
QPPPA
56
PAPRR
61
ERRDL
66
PAEPA
71
AARGG
76
GGGGG
81
GGGGG
86
RGPQA
91
RARGG
96
GPGEP
101
RGQQP
106
ASRGA
111
LPARA
116
LDPHP
121
SPLIT
126
LETQD
131
GYFSH
136
RPKEK
141
VRTDS
146
NNENS
151
VPKDF
156
ENVDN
161
SNFAP
166
RTQKQ
171
KHQPE
176
LAKKP
181
PSRQK
186
ELLKR
191
KLEQQ
196
EKGKG
201
HTFPG
206
KGPGE
211
VLPPG
216
DRAAA
221
NSSHG
226
KDVSR
231
PPHAR
236
KTGGS
241
SPETK
246
YDQPP
251
KCDIS
256
GKEAI
261
SALSR
266
AKSKH
271
CRQEI
276
GETYC
281
RHKLG
286
LLMPE
291
KVTRF
296
CPLEG
301
KANKN
306
VQWDE
311
DSVEY
316
MPANP
321
VRIAF
326
VLVVH
331
GRASR
336
QLQRM
341
FKAIY
346
HKDHF
351
YYIHV
356
DKRSN
361
YLHRQ
366
VLQVS
371
RQYSN
376
VRVTP
381
WRMAT
386
IWGGA
391
SLLST
396
YLQSM
401
RDLLE
406
MTDWP
411
WDFFI
416
NLSAA
421
DYPIR
426
TNDQL
431
VAFLS
436
RYRDM
441
NFLKS
446
HGRDN
451
ARFIR
456
KQGLD
461
RLFLE
466
CDAHM
471
WRLGD
476
RRIPE
481
GIAVD
486
GGSDW
491
FLLNR
496
RFVEY
501
VTFST
506
DDLVT
511
KMKQF
516
YSYTL
521
LPAES
526
FFHTV
531
LENSP
536
HCDTM
541
VDNNL
546
RITNW
551
NRKLG
556
CKCQY
561
KHIVD
566
WCGCS
571
PNDFK
576
PQDFH
581
RFQQT
586
ARPTF
591
FARKF
596
EAVVN
601
QEIIG
606
QLDYY
611
LYGNY
616
PAGTP
621
GLRSY
626
WENVY
631
DEPDG
636
IHSLS
641
DVTLT
646
LYHSF
651
ARLGL
656
RRAET
661
SLHTD
666
GENSC
671
RYYPM
676
GHPAS
681
VHLYF
686
LADRF
691
QGFLI
696
KHHAT
701
NLAVS
706
KLETL
711
ETWVM
716
PKKVF
721
KIASP
726
PSDFG
731
RLQFS
736
EVGTD
741
WDAKE
746
RLFRN
751
FGGLL
756
GPMDE
761
PVGMQ
766
KWGKG
771
PNVTV
776
TVIWV
781
DPVNV
786
IAATY
791
DILIE
796
STAEF
801
THYKP
806
PLNLP
811
LRPGV
816
WTVKI
821
LHHWV
826
PVAET
831
KFLVA
836
PLTFS
841
NRQPI
846
KPEEA
851
LKLHN
856
GPLRN
861
AYMEQ
866
SFQSL
871
NPVLS
876
LPINP
881
AQVEQ
886
ARRNA
891
ASTGT
896
ALEGW
901
LDSLV
906
GGMWT
911
AMDIC
916
ATGPT
921
ACPVM
926
QTCSQ
931
TAWSS
936
FSPDP
941
KSELG
946
AVKPD
951
GRLR
956
Mutation Information
DNA mutation:
None
Peptide Range:
338 ~ 362
Mut AA position:
350 (13 in Wild Type peptide)
Alignment
Wild Type:
"ASRQLQRMFKAIYHKDHFYYIHVDK
||||||||||||.||||||||||||
Mutant:
ASRQLQRMFKAINHKDHFYYIHVDK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) XYLT1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay