Immunogenicity 2107

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PCDHA1
Transcript ID
ENST00000378133
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (807 aa)
MVFSR
1
RGGLG
6
ARDLL
11
LWLLL
16
LAAWE
21
VGSGQ
26
LHYSI
31
PEEAK
36
HGTFV
41
GRVAQ
46
DLGLE
51
LAELV
56
PRLFR
61
VASKT
66
HRDLL
71
EVNLQ
76
NGILF
81
VNSRI
86
DREEL
91
CQWSA
96
ECSIH
101
LELIA
106
DRPLQ
111
VFHVE
116
VKVKD
121
INDNP
126
PVFRG
131
REQII
136
FIPES
141
RLLNS
146
RFPIE
151
GAADA
156
DIGAN
161
ALLTY
166
TLSPS
171
DYFSL
176
DVEAS
181
DELSK
186
SLWLE
191
LRKYL
196
DREET
201
PELHL
206
LLTAT
211
DGGKP
216
ELQGT
221
VELLI
226
TVLDV
231
NDNAP
236
LFDQA
241
VYRVH
246
LLETT
251
ANGTL
256
VTTLN
261
ASDAD
266
EGVNG
271
EVVFS
276
FDSGI
281
SRDIQ
286
EKFKV
291
DSSSG
296
EIRLI
301
DKLDY
306
EETKS
311
YEIQV
316
KAVDK
321
GSPPM
326
SNHCK
331
VLVKV
336
LDVND
341
NAPEL
346
AVTSL
351
YLPIR
356
EDAPL
361
STVIA
366
LITVS
371
DRDSG
376
ANGQV
381
TCSLM
386
PHVPF
391
KLVST
396
FKNYY
401
SLVLD
406
SALDR
411
ESLSV
416
YELVV
421
TARDG
426
GSPSL
431
WATAR
436
VSVEV
441
ADVND
446
NAPAF
451
AQPEY
456
TVFVK
461
ENNPP
466
GCHIF
471
TVSAR
476
DADAQ
481
ENALV
486
SYSLV
491
ERRVG
496
ERALS
501
NYVSV
506
HAESG
511
KVYAL
516
QPLDH
521
EELEL
526
LQFQV
531
SARDA
536
GVPPL
541
GSNVT
546
LQVFV
551
LDEND
556
NAPAL
561
LAPRV
566
GGTIG
571
AVSEL
576
VPRLV
581
GAGHV
586
VAKVR
591
AVDAD
596
SGYNA
601
WLSYE
606
LQPAA
611
GGARI
616
PFRVG
621
LYTGE
626
ISTTR
631
VLDEA
636
DLSRY
641
RLLVL
646
VKDHG
651
EPALT
656
ATATV
661
LVSLV
666
ESGQA
671
PKASS
676
RASVG
681
VAGPE
686
AALVD
691
VNVYL
696
IIAIC
701
AVSSL
706
LVLTL
711
LLYTA
716
LRCSV
721
PPTEG
726
AYVPG
731
KPTLV
736
CSSAL
741
GSWSN
746
SQQRR
751
QRVCS
756
SEGPP
761
KTDLM
766
AFSPG
771
LSPSL
776
NTSER
781
NEQPE
786
ANLDL
791
SGNVS
796
PTFEF
801
WL
806
Mutation Information
DNA mutation:
None
Peptide Range:
230 ~ 254
Mut AA position:
242 (13 in Wild Type peptide)
Alignment
Wild Type:
"ITVLDVNDNAPLFDQAVYRVHLLET
||||||||||||.||||||||||||
Mutant:
ITVLDVNDNAPLLDQAVYRVHLLET"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PCDHA1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay