Immunogenicity 2130

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
PLEKHG6
Transcript ID
ENST00000304581
HLA INFO
C*01:02
TCR INFO

No TCR info found!

T cell Tumor cell C*01:02
sequence
Full length protein sequence (320 aa)
MCPRE
1
GGRAS
6
TIHQK
11
TEKAF
16
GQLLC
21
QPLGE
26
PKIQH
31
PLKAA
36
LQKLK
41
AEEYV
46
QQKRE
51
LLTLY
56
RDQDR
61
ESPST
66
RPSTP
71
SLEGS
76
QSSAE
81
GRTPE
86
FSTII
91
PHLVV
96
TEDTD
101
EDAPL
106
VPDDT
111
SDSGY
116
GTLIP
121
GTPTG
126
SRSPL
131
SRLRQ
136
RALRR
141
DPRLT
146
FSTLE
151
LRDIP
156
LRPHP
161
PDPQA
166
PQRRS
171
APELP
176
EGILK
181
GGSLP
186
QEDPP
191
TWSEE
196
EDGAS
201
ERGNV
206
VVETL
211
HRARL
216
RGQLP
221
SSPTH
226
ADSAG
231
ESPWE
236
SSGEE
241
EEEGP
246
LFLKA
251
GHTSL
256
RPMRA
261
EDMLR
266
EIREE
271
LASQR
276
IEGAE
281
EPRDS
286
RPRKL
291
TRAQL
296
QRMRG
301
PHIIQ
306
LDTPL
311
SASEV
316
Mutation Information
DNA mutation:
None
Peptide Range:
116 ~ 140
Mut AA position:
128 (13 in Wild Type peptide)
Alignment
Wild Type:
"SDSGYGTLIPGTPTGSRSPLSRLRQ
||||||||||||.||||||||||||
Mutant:
SDSGYGTLIPGTSTGSRSPLSRLRQ"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PLEKHG6

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay