Immunogenicity 2153

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
OR5L1
Transcript ID
ENST00000333973
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (311 aa)
MGKEN
1
CTTVA
6
EFILL
11
GLSDV
16
PELRV
21
CLFLL
26
FLLIY
31
GVTLL
36
ANLGM
41
IALIQ
46
VSSRL
51
HTPMY
56
FFLSH
61
LSSVD
66
FCYSS
71
IIVPK
76
MLANI
81
FNKDK
86
AISFL
91
GCMVQ
96
FYLFC
101
TCVVT
106
EVFLL
111
AVMAY
116
DRFVA
121
ICNPL
126
LYTVT
131
MSWKV
136
RVELA
141
SCCYF
146
CGTVC
151
SLIHL
156
CLALR
161
IPFYR
166
SNVIN
171
HFFCD
176
LPPVL
181
SLACS
186
DITVN
191
ETLLF
196
LVATL
201
NESVT
206
IMIIL
211
TSYLL
216
ILTTI
221
LKMGS
226
AEGRH
231
KAFST
236
CASHL
241
TAITV
246
FHGTV
251
LSIYC
256
RPSSG
261
NSGDA
266
DKVAT
271
VFYTV
276
VIPML
281
NSVIY
286
SLRNK
291
DVKEA
296
LRKVM
301
GSKIH
306
S
311
Mutation Information
DNA mutation:
None
Peptide Range:
274 ~ 298
Mut AA position:
286 (13 in Wild Type peptide)
Alignment
Wild Type:
"ATVFYTVVIPMLNSVIYSLRNKDVK
||||||||||||.||||||||||||
Mutant:
ATVFYTVVIPMLSSVIYSLRNKDVK"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) OR5L1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay