Immunogenicity 2184

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
NBPF1
Transcript ID
ENST00000430580
HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
sequence
Full length protein sequence (1139 aa)
MVVSA
1
GPWSS
6
EKAET
11
NILEI
16
NEKLR
21
PQLAE
26
NKQQF
31
RNLKE
36
KCFVT
41
QLAGF
46
LANRQ
51
KKYKY
56
EECKD
61
LIKFM
66
LRNER
71
QFKEE
76
KLAEQ
81
LKQAE
86
ELRQY
91
KVLVH
96
SQERE
101
LTQLR
106
EKLRE
111
GRDAS
116
RSLNQ
121
HLQAL
126
LTPDK
131
PDKSQ
136
GQDLQ
141
EQLAE
146
GCRLA
151
QQLFQ
156
KLSPE
161
NDEDE
166
DEDVQ
171
VEEAE
176
KVLES
181
SAPRE
186
VQKAE
191
ESKVP
196
EDSLE
201
ECAIT
206
CSNSH
211
SPCDS
216
NQPHK
221
NINIT
226
FEEDK
231
VNSTL
236
VVDRE
241
SSHDE
246
CQDAV
251
NILPV
256
PGPTS
261
SATNV
266
SMVVS
271
AGPLS
276
SEKAE
281
MNILE
286
INEKL
291
HPQLA
296
EKKQQ
301
FRNLK
306
EKCFV
311
TQLAC
316
FLANQ
321
QNKYK
326
YEECK
331
DLIKS
336
MLRNE
341
RQFKE
346
EKLAE
351
QLKQA
356
EELRQ
361
YKVLV
366
HSQER
371
ELTQL
376
REKLR
381
EGRDA
386
SRSLN
391
QHLQA
396
LLTPD
401
KPDKS
406
QGQDL
411
QEQLA
416
EGCRL
421
AQQLF
426
QKLSP
431
ENDED
436
EDEDV
441
QVEEA
446
EKVLE
451
SSAPR
456
EVQKA
461
EESKV
466
PEDSL
471
EECAI
476
TCSNS
481
HGPCD
486
SNQPH
491
KNINI
496
TFEED
501
KVNSA
506
LVVDR
511
ESSHD
516
ECQDA
521
VNILP
526
VPGPT
531
SSATN
536
VSMVV
541
SAGPL
546
SSEKA
551
EMNIL
556
EINEK
561
LHPQL
566
AEKKQ
571
QFRNL
576
KEKCF
581
VTQLA
586
CFLAN
591
QQNKY
596
KNEEC
601
KDLIK
606
SMLRN
611
ERQFK
616
EEKLA
621
EQLKQ
626
AEELR
631
QYKVL
636
VHSQE
641
RELTQ
646
LREKL
651
REGRD
656
ASCSL
661
NQHLQ
666
ALLTP
671
DEPDK
676
SQGQD
681
LQEQL
686
AEGCR
691
LAQHL
696
VQKLS
701
PENDN
706
DDDED
711
VQVEV
716
AEKVQ
721
KSSAP
726
REMPK
731
AEEKE
736
VPEDS
741
LEECA
746
ITCSN
751
SHGPY
756
DSNQP
761
HRKTK
766
ITFEE
771
DKVDS
776
TLIGS
781
SSHVE
786
WEDAV
791
HIIPE
796
NESDD
801
EEEEE
806
KGPVS
811
PRNLQ
816
ESEEE
821
EVPQE
826
SWDEG
831
YSTLS
836
IPPEM
841
LASYK
846
SYSGT
851
FHSLE
856
EQQVC
861
MAVDI
866
GGHRW
871
DQVKK
876
EDQEA
881
TGPRL
886
SRELL
891
DEKGP
896
EVLQD
901
SLDRC
906
YSTPS
911
GYLEL
916
TDSCQ
921
PYRSA
926
FYILE
931
QQRVG
936
WALDM
941
DEIEK
946
YQEVE
951
EDQDP
956
SCPRL
961
SRELL
966
EAVEP
971
EVLQD
976
SLDRC
981
YSTPS
986
SCLEQ
991
PDSCL
996
PYGSS
1001
FYALE
1006
EKHVG
1011
FSLDV
1016
GEIEK
1021
KGKGK
1026
KRRGR
1031
RSTKK
1036
RRRRG
1041
RKEGE
1046
EDQNP
1051
PCPRL
1056
SGMLM
1061
EVEEP
1066
EVLQD
1071
SLDRC
1076
YSTPS
1081
MYFEL
1086
PDSFQ
1091
HYRSV
1096
FYSFE
1101
EQHIS
1106
FALDV
1111
DNRFL
1116
TLMGT
1121
SLHLV
1126
FQMGV
1131
IFPQ
1136
Mutation Information
DNA mutation:
None
Peptide Range:
1037 ~ 1061
Mut AA position:
1049 (13 in Wild Type peptide)
Alignment
Wild Type:
"STKKRRRRGRKEGEEDQNPPCPRLS
||||||||||||.||||||||||||
Mutant:
STKKRRRRGRKEREEDQNPPCPRLS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000219481

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay