Immunogenicity 2188

summary
Sample ID
3978
Response
Negative
Tumor Type
Bile duct cancer
Gene Symbol
HDGFL2
Transcript ID
ENST00000301284
HLA INFO
DQA*03:01 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*03:01 DQB*03:02
sequence
Full length protein sequence (676 aa)
MPHAF
1
KPGDL
6
VFAKM
11
KGYPH
16
WPARI
21
DDIAD
26
GAVKP
31
PPNKY
36
PIFFF
41
GTHET
46
AFLGP
51
KDLFP
56
YDKCK
61
DKYGK
66
PNKRK
71
GFNEG
76
LWEIQ
81
NNPHA
86
SYSAP
91
PPVSS
96
SDSEA
101
PEANP
106
ADGSD
111
ADEDD
116
EDRGV
121
MAVTA
126
VTATA
131
ASDRM
136
ESDSD
141
SDKSS
146
DNSGL
151
KRKTP
156
ALKMS
161
VSKRA
166
RKASS
171
DLDQA
176
SVSPS
181
EEENS
186
ESSSE
191
SEKTS
196
DQDFT
201
PEKKA
206
AVRAP
211
RRGPL
216
GGRKK
221
KKAPS
226
ASDSD
231
SKADS
236
DGAKP
241
EPVAM
246
ARSAS
251
SSSSS
256
SSSSD
261
SDVSV
266
KKPPR
271
GRKPA
276
EKPLP
281
KPRGR
286
KPKPE
291
RPPSS
296
SSSDS
301
DSDEV
306
DRISE
311
WKRRD
316
EARRR
321
ELEAR
326
RRREQ
331
EEELR
336
RLREQ
341
EKEEK
346
ERRRE
351
RADRG
356
EAERG
361
SGGSS
366
GDELR
371
EDDEP
376
VKKRG
381
RKGRG
386
RGPPS
391
SSDSE
396
PEAEL
401
EREAK
406
KSAKK
411
PQSSS
416
TEPAR
421
KPGQK
426
EKRVR
431
PEEKQ
436
QAKPV
441
KVERT
446
RKRSE
451
GFSMD
456
RKVEK
461
KKEPS
466
VEEKL
471
QKLHS
476
EIKFA
481
LKVDS
486
PDVKR
491
CLNAL
496
EELGT
501
LQVTS
506
QILQK
511
NTDVV
516
ATLKK
521
IRRYK
526
ANKDV
531
MEKAA
536
EVYTR
541
LKSRV
546
LGPKI
551
EAVQK
556
VNKAG
561
MEKEK
566
AEEKL
571
AGEEL
576
AGEEL
581
AGEEA
586
PQEKA
591
EDKPS
596
TDLSA
601
PVNGE
606
ATSQK
611
GESAE
616
DKEHE
621
EGRDS
626
EEGPR
631
CGSSE
636
DLHDS
641
VREGP
646
DLDRP
651
GSDRQ
656
ERERA
661
RGDSE
666
ALDEE
671
S
676
Mutation Information
DNA mutation:
None
Peptide Range:
233 ~ 257
Mut AA position:
245 (13 in Wild Type peptide)
Alignment
Wild Type:
"DSDSKADSDGAKPEPVAMARSASSS
||||||||||||.||||||||||||
Mutant:
DSDSKADSDGAKSEPVAMARSASSS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HDGFRP2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay