Immunogenicity 2197

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
JPH2
Transcript ID
ENST00000372980
HLA INFO
DQA*05:01 / DQB*06:03
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*05:01 DQB*06:03
sequence
Full length protein sequence (696 aa)
MSGGR
1
FDFDD
6
GGAYC
11
GGWEG
16
GKAHG
21
HGLCT
26
GPKGQ
31
GEYSG
36
SWNFG
41
FEVAG
46
VYTWP
51
SGNTF
56
EGYWS
61
QGKRH
66
GLGIE
71
TKGRW
76
LYKGE
81
WTHGF
86
KGRYG
91
IRQSS
96
SSGAK
101
YEGTW
106
NNGLQ
111
DGYGT
116
ETYAD
121
GGTYQ
126
GQFTN
131
GMRHG
136
YGVRQ
141
SVPYG
146
MAVVV
151
RSPLR
156
TSLSS
161
LRSEH
166
SNGTV
171
APDSP
176
ASPAS
181
DGPAL
186
PSPAI
191
PRGGF
196
ALSLL
201
ANAEA
206
AARAP
211
KGGGL
216
FQRGA
221
LLGKL
226
RRAES
231
RTSVG
236
SQRSR
241
VSFLK
246
SDLSS
251
GASDA
256
ASTAS
261
LGEAA
266
EGADE
271
AAPFE
276
ADIDA
281
TTTET
286
YMGEW
291
KNDKR
296
SGFGV
301
SERSS
306
GLRYE
311
GEWLD
316
NLRHG
321
YGCTT
326
LPDGH
331
REEGK
336
YRHNV
341
LVKDT
346
KRRML
351
QLKSN
356
KVRQK
361
VEHSV
366
EGAQR
371
AAAIA
376
RQKAE
381
IAASR
386
TSHAK
391
AKAEA
396
AEQAA
401
LAANQ
406
ESNIA
411
RTLAR
416
ELAPD
421
FYQPG
426
PEYQK
431
RRLLQ
436
EILEN
441
SESLL
446
EPPDR
451
GAGAA
456
GLPQP
461
PRESP
466
QLHER
471
ETPRP
476
EGGSP
481
SPAGT
486
PPQPK
491
RPRPG
496
VSKDG
501
LLSPG
506
AWNGE
511
PSGEG
516
SRSVT
521
PSEGA
526
GRRSP
531
ARPAT
536
ERMAI
541
EALQA
546
PPAPS
551
REPEV
556
ALYQG
561
YHSYA
566
VRTTP
571
PEPPP
576
FEDQP
581
EPEVS
586
GSESA
591
PSSPA
596
TAPLQ
601
APTLR
606
GPEPA
611
RETPA
616
KLEPK
621
PIIPK
626
AEPRA
631
KARKT
636
EARGL
641
TKAGA
646
KKKAR
651
KEAAL
656
AAEAE
661
VEVEE
666
VPNTI
671
LICMV
676
ILLNI
681
GLAIL
686
FVHLL
691
T
696
Mutation Information
DNA mutation:
None
Peptide Range:
169 ~ 193
Mut AA position:
181 (13 in Wild Type peptide)
Alignment
Wild Type:
"EHSNGTVAPDSPASPASDGPALPSP
||||||||||||.||||||||||||
Mutant:
EHSNGTVAPDSPTSPASDGPALPSP"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) JPH2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay