Immunogenicity 2225

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KIAA0895L
Transcript ID
ENST00000569349
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (160 aa)
MVLDS
1
GAQAY
6
DQAPW
11
DGLHL
16
DGDGT
21
QVGAP
26
CGLQP
31
PCLTL
36
LRLKG
41
MQAIL
46
PARAP
51
ACWWP
56
CGQPT
61
WTVSE
66
TSSSS
71
PITPT
76
IHSLS
81
TRSPC
86
PRLCW
91
KSTAR
96
PLDSS
101
SIRQL
106
ASLRL
111
FWRSL
116
EPMNT
121
LRLPL
126
GGSCS
131
PSARY
136
GRLCA
141
NTCRR
146
RAALG
151
RLWCS
156
Mutation Information
DNA mutation:
None
Peptide Range:
80 ~ 104
Mut AA position:
92 (13 in Wild Type peptide)
Alignment
Wild Type:
"TIHSLSTRSPCPRLCWKSTARPLDS
||||||||||||.||||||||||||
Mutant:
TIHSLSTRSPCPQLCWKSTARPLDS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000196123

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay