Immunogenicity 2232

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
CACNB3
Transcript ID
ENST00000547392
HLA INFO
DRB*15:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*15:01
sequence
Full length protein sequence (457 aa)
MYDDS
1
YVPGF
6
EDSEA
11
GSADS
16
YTSRP
21
SLDSD
26
VSLEE
31
DRESA
36
RREVE
41
SQAQQ
46
QLERA
51
KHKPV
56
AFAVR
61
TNVSY
66
CGVLD
71
EECPV
76
QGSGV
81
NFEAK
86
DFLHI
91
KEKYS
96
NDWWI
101
GRLVK
106
EGGDI
111
AFIPS
116
PQRLE
121
SIRLK
126
QEQKA
131
RRSGN
136
PSSLS
141
DIGNR
146
RSPPP
151
SLAKQ
156
KQKQV
161
TDMMQ
166
KALFD
171
FLKHR
176
FDGRI
181
SITRV
186
TADLS
191
LAKRS
196
VLNNP
201
GKRTI
206
IERSS
211
ARSSI
216
AEVQS
221
EIERI
226
FELAK
231
SLQLV
236
VLDAD
241
TINHP
246
AQLAK
251
TSLAP
256
IIVFV
261
KVSSP
266
KVLQR
271
LIRSR
276
GKSQM
281
KHLTV
286
QMMAY
291
DKLVQ
296
CPPES
301
FDVIL
306
DENQL
311
EDACE
316
HLAEY
321
LEVYW
326
RATHH
331
PAPGP
336
GLLGP
341
PSAIP
346
GLQNQ
351
QLLGE
356
RGEEH
361
SPLER
366
DSLMP
371
SDEAS
376
ESSRQ
381
AWTGS
386
SQRSS
391
RHLEE
396
DYADA
401
YQDLY
406
QPHRQ
411
HTSGL
416
PSANG
421
HDPQD
426
RLLAQ
431
DSEHN
436
HSDRN
441
WQRNR
446
PWPKD
451
SY
456
Mutation Information
DNA mutation:
None
Peptide Range:
155 ~ 179
Mut AA position:
167 (13 in Wild Type peptide)
Alignment
Wild Type:
"PSLAKQKQKQVTDMMQKALFDFLKH
||||||||||||.||||||||||||
Mutant:
PSLAKQKQKQVTEMMQKALFDFLKH"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000167535

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay