Immunogenicity 2240

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
KRAS
Transcript ID
ENST00000256078
HLA INFO
DRB*03:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*03:01
sequence
Full length protein sequence (189 aa)
MTEYK
1
LVVVG
6
AGGVG
11
KSALT
16
IQLIQ
21
NHFVD
26
EYDPT
31
IEDSY
36
RKQVV
41
IDGET
46
CLLDI
51
LDTAG
56
QEEYS
61
AMRDQ
66
YMRTG
71
EGFLC
76
VFAIN
81
NTKSF
86
EDIHH
91
YREQI
96
KRVKD
101
SEDVP
106
MVLVG
111
NKCDL
116
PSRTV
121
DTKQA
126
QDLAR
131
SYGIP
136
FIETS
141
AKTRQ
146
RVEDA
151
FYTLV
156
REIRQ
161
YRLKK
166
ISKEE
171
KTPGC
176
VKIKK
181
CIIM
186
Mutation Information
DNA mutation:
None
Peptide Range:
134 ~ 158
Mut AA position:
146 (13 in Wild Type peptide)
Alignment
Wild Type:
"ARSYGIPFIETSAKTRQRVEDAFYT
||||||||||||.||||||||||||
Mutant:
ARSYGIPFIETSVKTRQRVEDAFYT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) KRAS

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay