Immunogenicity 2252

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
PDE4DIP
Transcript ID
ENST00000369348
HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
sequence
Full length protein sequence (310 aa)
MKGTD
1
SGSCC
6
RRRCD
11
FGCCC
16
RASRR
21
AHYTP
26
YRSGD
31
ATRTP
36
QSPRQ
41
TPSRE
46
RRRPE
51
PAGSW
56
AAAAE
61
EEEAA
66
AAATP
71
WMRDY
76
FAEDD
81
GEMVP
86
RTSHT
91
AAFLS
96
DTKDR
101
GPPVQ
106
SQIWR
111
SGEKV
116
PFVQT
121
YSLRA
126
FEKPP
131
QVQTQ
136
ALRDF
141
EKHLN
146
DLKKE
151
NFSLK
156
LRIYF
161
LEERM
166
QQKYE
171
ASRED
176
IYKRN
181
IELKV
186
EVESL
191
KRELQ
196
DKKQH
201
LDKTW
206
ADVEN
211
LNSQN
216
EAELR
221
RQFEE
226
RQQET
231
EHVYE
236
LLENK
241
IQLLQ
246
EESRL
251
AKNEA
256
ARMAA
261
LVEAE
266
KECNL
271
ELSEK
276
LKGVT
281
KNWED
286
VPGDQ
291
VKPDQ
296
YTEAL
301
AQRDK
306
Mutation Information
DNA mutation:
None
Peptide Range:
12 ~ 36
Mut AA position:
24 (13 in Wild Type peptide)
Alignment
Wild Type:
"RRCDFGCCCRASRRAHYTPYRSGDA
||||||||||||.||||||||||||
Mutant:
RRCDFGCCCRASLRAHYTPYRSGDA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) PDE4DIP

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay