Immunogenicity 2346
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
IGFN1
Transcript ID
ENST00000335211
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (3708 aa)
MAGKL
1
RKSHI
6
PGVSI
11
WQLVE
16
EIPEG
21
CSTPD
26
FEQKP
31
VTSAL
36
PEGKN
41
AVFRA
46
VVCGE
51
PRPEV
56
RWQNS
61
KGDLS
66
DSSKY
71
KISSS
76
PGSKE
81
HVLQI
86
NKLTG
91
EDTDL
96
YRCTA
101
VNAYG
106
EAACS
111
VRLTV
116
IEVGF
121
RKNRK
126
RHREP
131
QEDLR
136
KELMD
141
FRKLL
146
KKRAP
151
PAPKK
156
KMDLE
161
QIWQL
166
LMTAD
171
RKDYE
176
KICLK
181
YGIVD
186
YRGML
191
RRLQE
196
MKKEQ
201
EDKMA
206
QYINT
211
ISSLR
216
HIRVT
221
KDGNA
226
KFDLE
231
LDLKD
236
SQSKI
241
YLYKD
246
GEMIP
251
YGFNN
256
QTKHC
261
LRRLG
266
KRYEF
271
QIQDL
276
RPEDS
281
GIYQV
286
KVEDA
291
VVFST
296
ELEAS
301
AIPPR
306
VVVPL
311
AETHC
316
EEQGD
321
AVFEC
326
TLSSP
331
CPSAA
336
WHFRH
341
RLLHP
346
SDKYE
351
VYVSP
356
DGLTH
361
RLVVR
366
GARFS
371
DMGPY
376
SLGTG
381
LYTSS
386
AWLVV
391
EAGKD
396
KDLQS
401
TSADH
406
KLQRQ
411
GAQAS
416
GAEES
421
GSIES
426
QGEKS
431
REQGP
436
RGGSL
441
EGAGP
446
ASGLQ
451
HIASP
456
DRDGL
461
GRHGY
466
SLMGD
471
KGTAD
476
SAWGP
481
GQEGE
486
GFPVA
491
EGSRA
496
TLPRE
501
NQSHR
506
EGGWA
511
RSLAE
516
RPHLQ
521
GESSE
526
SGLGL
531
PEKQQ
536
QDRGR
541
DSNSD
546
ECWRK
551
AGGWE
556
AGSSR
561
LQAGG
566
LGSSR
571
EGKEH
576
RGDSG
581
RQLDR
586
HAPEQ
591
LWDAR
596
LGPGR
601
GKSDL
606
QGCQS
611
DPVGS
616
WPRGK
621
QIEIS
626
QDDSL
631
AEMDR
636
GDAPS
641
RERGR
646
GIVVW
651
GGGTG
656
LGEAG
661
DSNGA
666
GGPGT
671
LELTG
676
GRGSG
681
SKVGM
686
APESW
691
GSQGG
696
RDADY
701
GEARG
706
YWGSG
711
ELLEQ
716
IPGGK
721
DFQEP
726
SISGG
731
RKFLL
736
GDGSP
741
EIKAE
746
DSLQE
751
ADGIC
756
RGESV
761
VTGSA
766
YKTGP
771
GGPGD
776
PRGCE
781
GVLQE
786
LRGRD
791
GQETA
796
WASGE
801
VEYDP
806
RSFQS
811
SQGWT
816
AGHRA
821
AGGIG
826
RIESK
831
GTSPW
836
DDTPS
841
SLRKT
846
GAHHG
851
PGVLG
856
PSGGQ
861
EGMGG
866
IWVAG
871
LTESG
876
QGVDA
881
RSHWL
886
SRAPG
891
LGAQG
896
SGGTL
901
GDKKG
906
LRGPG
911
SIGSE
916
PDFWN
921
GSGSS
926
RVKGP
931
RGETG
936
YKDGL
941
EGPGR
946
MESRY
951
EGGLG
956
YSREI
961
SSKSG
966
AGYSY
971
GSGVP
976
GEMGS
981
GHGAG
986
CRVSP
991
RAPAG
996
VESEE
1001
GGGYR
1006
HGSGA
1011
PGGVW
1016
SGNED
1021
SGPAG
1026
GGSGR
1031
VASLK
1036
NGSGG
1041
PDGAP
1046
MNDTR
1051
NWASA
1056
CQAGM
1061
DPRGG
1066
HHSDG
1071
GLGSP
1076
GVTGS
1081
AGRGG
1086
LKAPG
1091
VVETV
1096
GMGCV
1101
EAEPE
1106
SSGRI
1111
RPWGQ
1116
TGNYG
1121
GFRAS
1126
EALGA
1131
FGEGG
1136
YEDGS
1141
GGPGA
1146
MGPGS
1151
LRAGS
1156
KVGEG
1161
DGTRC
1166
PGAKA
1171
SGAGA
1176
GYRDD
1181
TRHPE
1186
SLAPH
1191
NGAAS
1196
GSQWA
1201
YGAGN
1206
VLGYE
1211
DGSEL
1216
PGPQG
1221
TGVRT
1226
AYGER
1231
SRGLG
1236
PRSTG
1241
PGGEA
1246
GFRDG
1251
SGGLQ
1256
GMGSA
1261
DGPGC
1266
RKGIG
1271
SSGEM
1276
GSVDK
1281
EGYKK
1286
DLGAP
1291
ENMGS
1296
GSKAD
1301
YRDGV
1306
GGSGA
1311
MGSMD
1316
EAGYR
1321
KDLGA
1326
PEGIS
1331
SGSKA
1336
DYRGG
1341
LQDSR
1346
EAGSG
1351
SKADY
1356
SGGLK
1361
GSREI
1366
GSMDE
1371
TDNRK
1376
DLGVP
1381
EGMGA
1386
GYRAG
1391
LRGPG
1396
EMGSL
1401
DESGH
1406
RNGIG
1411
GYGEM
1416
GSGYR
1421
EDLGA
1426
PEGMG
1431
TGSKA
1436
GYRDG
1441
LRGSG
1446
EMRSM
1451
DEAGY
1456
RKNLG
1461
APERM
1466
DSGSK
1471
AGYRG
1476
GLRGS
1481
GEMGL
1486
IEAGY
1491
RKDLG
1496
VSEGG
1501
GSGSK
1506
AGYRG
1511
GLGSG
1516
EMGSV
1521
DKAGY
1526
RKDLG
1531
ASEAI
1536
GSGSK
1541
AGFTD
1546
GLGGS
1551
EEMGS
1556
VNKAG
1561
YRKDL
1566
GAPKG
1571
MGSGS
1576
KASFR
1581
DGLGG
1586
SGEMG
1591
SVNEA
1596
GYRKD
1601
LGVPE
1606
GIGSG
1611
SKAGF
1616
RDGLG
1621
GSEEM
1626
GSVNK
1631
AGYRK
1636
DLGAP
1641
KGIGS
1646
GSKAG
1651
FRDGL
1656
GSSGE
1661
MGSMD
1666
EAGYR
1671
KNLGA
1676
PEGIG
1681
SGSKA
1686
GFRDG
1691
LGSSV
1696
EMGSV
1701
NEAGY
1706
RKDLG
1711
APEGM
1716
GSGSK
1721
AGFRD
1726
GLGGS
1731
GEMGS
1736
VNEAG
1741
YRKDL
1746
GAPKG
1751
IGSGS
1756
KADFR
1761
DALGS
1766
SGEMG
1771
SMDEA
1776
GYRKD
1781
LWAPE
1786
GIGSG
1791
SKAGF
1796
RDGLG
1801
SSVEM
1806
GSVNE
1811
AGYRK
1816
DLGAP
1821
EGMGS
1826
GSKAG
1831
FRDGL
1836
GGSGE
1841
MGSVN
1846
EAGYR
1851
KDLGA
1856
PKGIG
1861
SGSKA
1866
DFRDA
1871
LGSSG
1876
EMGSM
1881
DEAGY
1886
RKDLW
1891
APEGI
1896
GSGSK
1901
AGFRD
1906
GLGSS
1911
VEMGS
1916
VNEAG
1921
YRKDL
1926
GAPEG
1931
MGSGS
1936
KEGFR
1941
DGLGG
1946
SEEMG
1951
SVNKA
1956
GYRKD
1961
LGAPK
1966
GMGSG
1971
SKEGF
1976
RDGLG
1981
GSEEM
1986
GSMDE
1991
AGYRK
1996
DLGAP
2001
EGIGS
2006
GSKAG
2011
FRDGL
2016
GGSEE
2021
MRSMD
2026
EAGYR
2031
KDLGA
2036
PERIG
2041
SGSKA
2046
GFRDG
2051
LGSSV
2056
EMGSV
2061
NEAGY
2066
RKDLG
2071
APKGM
2076
GSGSK
2081
TGFRD
2086
GLGGS
2091
EEMES
2096
MDEAG
2101
YRKDL
2106
GAPEG
2111
IGSGS
2116
KAGFR
2121
DGLGS
2126
STEMG
2131
SVNEA
2136
GYRKD
2141
LGAPK
2146
GMGSE
2151
SKAGF
2156
RDGLG
2161
SSGEM
2166
GSMDE
2171
AGYRK
2176
DLGAP
2181
EGMGS
2186
GSKAG
2191
FRDGL
2196
GGSEE
2201
MGSVN
2206
KAGYR
2211
KDLGA
2216
PKGMG
2221
SGSKA
2226
GFRDG
2231
LGSSG
2236
EMGSM
2241
DEADY
2246
RKDLG
2251
APEEM
2256
GSGSY
2261
TDYRN
2266
GLGSS
2271
GKISS
2276
GDEAG
2281
YKNVL
2286
GGSGR
2291
NPLGS
2296
EAGSR
2301
GSLED
2306
SGYIL
2311
SWNEA
2316
GSRQG
2321
FGGTS
2326
GMGSG
2331
SEVSY
2336
RGGSG
2341
GSGET
2346
GPEGK
2351
MGYGD
2356
GSGRL
2361
GVPGS
2366
LAGIG
2371
HEAGP
2376
RGHKA
2381
MGHRS
2386
GYWVA
2391
SEGDT
2396
NSKDG
2401
PERAR
2406
ETRLV
2411
DGAGP
2416
GVEPG
2421
MAGMP
2426
GTAGG
2431
MAHRD
2436
SLRGT
2441
GVLGS
2446
QGGRQ
2451
TLSDE
2456
RGSTK
2461
DLGGY
2466
GTSGI
2471
PEASE
2476
AAGAK
2481
GKPDV
2486
KEWQD
2491
SSGTP
2496
GSSRD
2501
RGAPR
2506
VKDRS
2511
PDQAG
2516
IMGAS
2521
GFLDG
2526
KGAVE
2531
GETWA
2536
GMAAL
2541
GSGYE
2546
RDIWK
2551
AGPGM
2556
TDRGR
2561
VAGQG
2566
GLASQ
2571
GGGDS
2576
LLGGR
2581
RVGSG
2586
SSVGT
2591
GQDLD
2596
SGSMP
2601
GGRGK
2606
STSGP
2611
ADRQG
2616
TSNAW
2621
APDWE
2626
NQGFS
2631
QGSID
2636
AGKQP
2641
AGSRA
2646
SGSLQ
2651
EKDAA
2656
FGGTH
2661
EGPGG
2666
FKGGE
2671
GAPGQ
2676
EAAGG
2681
CRSPW
2686
SLDSK
2691
GSSPG
2696
RGSSV
2701
DAEDS
2706
GILGK
2711
GNSTE
2716
WGNAL
2721
TPKPG
2726
ESGPQ
2731
GAWNG
2736
LDGPF
2741
GRKAS
2746
RDRSG
2751
GTQDL
2756
SSQRG
2761
KGQRG
2766
GKRSL
2771
GEQGS
2776
LEAEN
2781
GEVQG
2786
PGALK
2791
EDEGQ
2796
GVEEA
2801
GRSGR
2806
RPGSL
2811
RSRSQ
2816
AQSGA
2821
EVGGG
2826
KRRGA
2831
DEAGS
2836
MGWQP
2841
MGENW
2846
GCLEE
2851
MLNED
2856
QSREP
2861
PGHLG
2866
SRRSG
2871
KDGRL
2876
DIYGE
2881
RRDAT
2886
RSSTS
2891
RYKPG
2896
TGSFS
2901
KDAQG
2906
PMGHF
2911
SQGLA
2916
DMEVQ
2921
PGEAA
2926
TLSCT
2931
LTSDL
2936
GPGTW
2941
FKDGV
2946
KLTTQ
2951
DGVIF
2956
KQDGL
2961
VHSLF
2966
ITHVQ
2971
GTQAG
2976
RYTFV
2981
AGDQQ
2986
SEATL
2991
TVQDS
2996
PTIAP
3001
DVTEK
3006
LREPL
3011
VVKAG
3016
KPVIV
3021
KIPFQ
3026
SHLPI
3031
QAAWR
3036
KDGAE
3041
VVGSS
3046
DREAQ
3051
VDLGD
3056
GYTRL
3061
CLPSA
3066
GRKDC
3071
GQYSV
3076
TLRSE
3081
GGSVQ
3086
AELTL
3091
QVIDK
3096
PDPPQ
3101
GPMEV
3106
QDCHR
3111
AGVCL
3116
RWRPP
3121
RDNGG
3126
RTVEC
3131
YVVER
3136
RQAGR
3141
STWLK
3146
VGEAP
3151
ADSTT
3156
FTDAH
3161
VEPGR
3166
KYTFR
3171
VRAVT
3176
SEGAG
3181
EALES
3186
EEILV
3191
APEAL
3196
PKAPS
3201
APAIL
3206
SASSQ
3211
GITLT
3216
WTAPR
3221
GPGSA
3226
HILGY
3231
LIERR
3236
KKGSN
3241
TWTAV
3246
NDQPV
3251
PERRW
3256
TVADV
3261
RQGCQ
3266
YEFRV
3271
TAVAP
3276
SGPGE
3281
PGPPS
3286
DAVFA
3291
RDPMR
3296
PPGLV
3301
RNLQV
3306
TDRSN
3311
TSITL
3316
SWAGP
3321
DTQEG
3326
DEAQG
3331
YVVEL
3336
CSSDS
3341
LQWLP
3346
CHVGT
3351
VPVTT
3356
YTAKG
3361
LRPGE
3366
GYFVR
3371
VTAVN
3376
EGGQS
3381
QPSAL
3386
DTLVQ
3391
AMPVT
3396
VCPKF
3401
LVDSS
3406
TKDLL
3411
TVKVG
3416
DTVRV
3421
PVSFE
3426
AMPMP
3431
EVTWL
3436
KDGLP
3441
LPKRS
3446
VTVTK
3451
DGLTQ
3456
LLIPV
3461
AGLSD
3466
SGLYT
3471
VVLRT
3476
LQGKE
3481
VAHSF
3486
RIRVA
3491
ACPQA
3496
PGPIH
3501
LQENV
3506
PGTVT
3511
AEWEP
3516
SPDEA
3521
QDVPL
3526
HYAVF
3531
TRSSA
3536
HGPWH
3541
EAADR
3546
IHTNR
3551
FTLLG
3556
ILPGH
3561
EYHFR
3566
VVAKN
3571
ELGAS
3576
KPSDT
3581
SQPWC
3586
IPRQR
3591
DRFTV
3596
KAPCY
3601
REPDL
3606
SQKPR
3611
FLVGL
3616
RSHLL
3621
PQGCE
3626
CCMSC
3631
AVQGS
3636
PRPHV
3641
TWFKN
3646
DRSLE
3651
GNPAV
3656
YSTDL
3661
LGVCS
3666
LTIPS
3671
VSPKD
3676
SGEYK
3681
AVAEN
3686
TLGQA
3691
VSTAT
3696
LIVIE
3701
PST
3706
Mutation Information
DNA mutation:
None
Peptide Range:
2082 ~ 2106
Mut AA position:
2094 (13 in Wild Type peptide)
Alignment
Wild Type:
"SGSKTGFRDGLGGSEEMESMDEAGY
||||||||||||.||||||||||||
Mutant:
SGSKTGFRDGLGSSEEMESMDEAGY"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) IGFN1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay