Immunogenicity 2361

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
C1orf127
Transcript ID
uc010oao.2
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (823 aa)
MWGSP
1
ALAWA
6
VWLAC
11
VQPTV
16
FPWSL
21
SFRSD
26
TDKPS
31
SAAEV
36
LTEAS
41
SCWTD
46
TVECF
51
SDYMT
56
LWIPR
61
SHVEG
66
LRRWL
71
ARTLH
76
LPGTW
81
RSPDH
86
LDSSL
91
AKCGY
96
FLHLA
101
SDGDF
106
LFRVQ
111
YSACF
116
VQKEK
121
ANYRL
126
EIRIF
131
QKGVM
136
GLERS
141
DRYIM
146
KCPML
151
RSRLG
156
QESVH
161
CGPMF
166
IQVSR
171
PLPLW
176
RDNRQ
181
TPWLL
186
SLRGE
191
LVASL
196
EDASL
201
MGLYV
206
DMNAT
211
TVTVQ
216
SPRQG
221
LLQRW
226
EVLNT
231
SAELL
236
PLWLV
241
SGHHA
246
YSLEA
251
ACPPV
256
SFQPE
261
SEVLV
266
HIPKQ
271
RLGLV
276
KRGSY
281
IEETL
286
SLRFL
291
RVHQS
296
NIFMV
301
TENKD
306
FVVVS
311
IPAAG
316
VLQVQ
321
RCQEV
326
GGTPG
331
TQAFY
336
RVDLS
341
LEFAE
346
MAAPV
351
LWTVE
356
SFFQC
361
VGSGT
366
ESPAS
371
TAALR
376
TTPSP
381
PSPGP
386
ETPPA
391
GVPPA
396
ASSQV
401
WAAGP
406
AAQEW
411
LSRDL
416
LHRPS
421
DALAK
426
KGLGP
431
FLQTA
436
KPARR
441
GQTSA
446
SILPR
451
VVQAQ
456
RGPQP
461
PPGEA
466
GIPGH
471
PTPPA
476
TLPSE
481
PVEGV
486
QASPW
491
RPRPV
496
LPTHP
501
ALTLP
506
VSSDA
511
SSPSP
516
PAPRP
521
ERPES
526
LLVSG
531
PSVTL
536
TEGLG
541
TVRPE
546
QDPAK
551
SPGSP
556
LLLRG
561
LSSGD
566
VAAPE
571
PIMGE
576
PGQAS
581
EEFQP
586
LARPW
591
RATLA
596
AEELV
601
SHRSP
606
GEPQE
611
TCSGT
616
EVERP
621
RQTGP
626
GLPRE
631
GARGH
636
MDLSS
641
SEPSQ
646
DIEGP
651
GLSIL
656
PARDA
661
TFSTP
666
SVRQP
671
DPSAW
676
LSSGP
681
ELTGM
686
PRVRL
691
AAPLA
696
VLPME
701
PLPPE
706
PVRPA
711
ALLTP
716
EASSV
721
GGPDQ
726
ARYLE
731
SAPGW
736
PVGQE
741
EWGVA
746
HTSSP
751
PSTQT
756
LSLWA
761
PTGVL
766
LPSLV
771
ELEYP
776
FQAGR
781
GASLQ
786
QELTE
791
PTLAL
796
SAESH
801
RPPEL
806
QDSVE
811
GLSER
816
PSR
821
Mutation Information
DNA mutation:
None
Peptide Range:
357 ~ 381
Mut AA position:
369 (13 in Wild Type peptide)
Alignment
Wild Type:
"WTVESFFQCVGSGTESPASTAALRT
||||||||||||.||||||||||||
Mutant:
WTVESFFQCVGSETESPASTAALRT"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) C1orf127

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay