Immunogenicity 2370

summary
Sample ID
4032
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
HNRNPCL1
Transcript ID
uc010obf.2
HLA INFO
A*03:01
TCR INFO

No TCR info found!

T cell Tumor cell A*03:01
sequence
Full length protein sequence (293 aa)
MASNV
1
TNKMD
6
PHSMN
11
SRVFI
16
GNLNT
21
LVVKK
26
SDVEA
31
IFSKY
36
GKIAG
41
CSVHK
46
GFAFV
51
QYDKE
56
KNARA
61
AVAGE
66
DGRMI
71
ASQVV
76
DINLA
81
AEPKV
86
NRGNA
91
GVKRS
96
AAEMY
101
GSSFD
106
LDYGF
111
QRDYY
116
DGMYS
121
FPARV
126
PPPPP
131
IALAV
136
VPSKR
141
QRLSG
146
NTSRR
151
GKSGF
156
NSKSG
161
KRGSS
166
KSGKL
171
KGDDL
176
QAIKQ
181
ELTQI
186
KQKVD
191
SLLEN
196
LEKIE
201
KEQSK
206
QEVEV
211
KNAKS
216
EEEQS
221
SSSMK
226
KDETH
231
VKMES
236
EGGAE
241
DSAEE
246
GDPLD
251
DDVNE
256
DQGDD
261
QLELI
266
KDDEK
271
EAEEG
276
EDDRD
281
STNGQ
286
DDS
291
Mutation Information
DNA mutation:
None
Peptide Range:
241 ~ 270
Mut AA position:
253 (13 in Wild Type peptide)
Alignment
Wild Type:
"EGGAEDSAEEGDPLDDDVNEDQGDD-----
||||||||||||.|.||.|||||||
Mutant:
EGGAEDSAEEGDLLTDDDNEDQGDDQLELI"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) HNRNPCL1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay