Immunogenicity 2400

summary
Sample ID
3948
Response
Negative
Tumor Type
Esophageal cancer
Gene Symbol
MECR
Transcript ID
uc001brq.1
HLA INFO
DQA*01:03 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*06:02
sequence
Full length protein sequence (373 aa)
MWVCS
1
TLWRV
6
RTPAR
11
QWRGL
16
LPASG
21
CHGPA
26
ASSYS
31
ASAEP
36
ARVRA
41
LVYGH
46
HGDPA
51
KVVEL
56
KNLEL
61
AAVRG
66
SDVRV
71
KMLAA
76
PINPS
81
DINMI
86
QGNYG
91
FLPEL
96
PAVGG
101
NEGVA
106
QVVAV
111
GSNVT
116
GLKPG
121
DWVIP
126
ANAGL
131
GTWRT
136
EAVFS
141
EEALI
146
QVPSD
151
IPLQS
156
AATLG
161
VNPCT
166
AYRML
171
MDFEQ
176
LQPGD
181
SVIQN
186
ASNSG
191
VGQAV
196
IQIAA
201
ALGLR
206
TINVV
211
RDRPD
216
IQKLS
221
DRLKS
226
LGAEH
231
VITEE
236
ELRRP
241
EMKNF
246
FKDMP
251
QPRLA
256
LNCVG
261
GKSST
266
ELLRQ
271
LARGG
276
TMVTY
281
GGMAK
286
QPVVA
291
SVSLL
296
IFKDL
301
KLRGF
306
WLSQW
311
KKDHS
316
PDQFK
321
ELILT
326
LCDLI
331
RRGQL
336
TAPAC
341
SQVPL
346
QDYQS
351
ALEAS
356
MKPFI
361
SSKQI
366
LTM
371
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 22
Mut AA position:
10 (10 in Wild Type peptide)
Alignment
Wild Type:
"MWVCSTLWRVRTPARQWRGLLPASG
|||||||||.||||||||||||
Mutant:
MWVCSTLWRGRTPARQWRGLLP---"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MECR

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay