Immunogenicity 2440

summary
Sample ID
4069
Response
Negative
Tumor Type
Pancreatic cancer
Gene Symbol
MPL
Transcript ID
uc001civ.3
HLA INFO
DQA*01:03 / DQB*03:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*03:02
sequence
Full length protein sequence (549 aa)
MPSWA
1
LFMVT
6
SCLLL
11
APQNL
16
AQVSS
21
QDVSL
26
LASDS
31
EPLKC
36
FSRTF
41
EDLTC
46
FWDEE
51
EAAPS
56
GTYQL
61
LYAYP
66
REKPR
71
ACPLS
76
SQSMP
81
HFGTR
86
YVCQF
91
PDQEE
96
VRLFF
101
PLHLW
106
VKNVF
111
LNQTR
116
TQRVL
121
FVDSV
126
GLPAP
131
PSIIK
136
AMGGS
141
QPGEL
146
QISWE
151
EPAPE
156
ISDFL
161
RYELR
166
YGPRD
171
PKNST
176
GPTVI
181
QLIAT
186
ETCCP
191
ALQRP
196
HSASA
201
LDQSP
206
CAQPT
211
MPWQD
216
GPKQT
221
SPSRE
226
ASALT
231
AEGGS
236
CLISG
241
LQPGN
246
SYWLQ
251
LRSEP
256
DGISL
261
GGSWG
266
SWSLP
271
VTVDL
276
PGDAV
281
ALGLQ
286
CFTLD
291
LKNVT
296
CQWQQ
301
QDHAS
306
SQGFF
311
YHSRA
316
RCCPR
321
DRYPI
326
WENCE
331
EEEKT
336
NPGLQ
341
TPQFS
346
RCHFK
351
SRNDS
356
IIHIL
361
VEVTT
366
APGTV
371
HSYLG
376
SPFWI
381
HQAVR
386
LPTPN
391
LHWRE
396
ISSGH
401
LELEW
406
QHPSS
411
WAAQE
416
TCYQL
421
RYTGE
426
GHQDW
431
KVLEP
436
PLGAR
441
GGTLE
446
LRPRS
451
RYRLQ
456
LRARL
461
NGPTY
466
QGPWS
471
SWSDP
476
TRVET
481
ATETA
486
WISLV
491
TALHL
496
VLGLS
501
AVLGL
506
LLLRW
511
QFPAH
516
YRYRP
521
RQAGD
526
WRWTR
531
WSRRP
536
VNRHS
541
WFAL
546
Mutation Information
DNA mutation:
None
Peptide Range:
524 ~ 548
Mut AA position:
536 (13 in Wild Type peptide)
Alignment
Wild Type:
"RPRQAGDWRWTRWSRRPVNRHSWFA
||||||||||||.||||||||||||
Mutant:
RPRQAGDWRWTRGSRRPVNRHSWFA"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MPL

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay